A Comparison of Xenograft Graft Material and Synthetic Bioactive Glass Allograft in Immediate Dental Implant Patients

Goutam, Manish; Batra, Namish; Jyothirmayee, K; Bagrecha, Nitin; Deshmukh, Poonam; Malik, Shalie

doi:10.4103/jpbs.jpbs_808_21

Cited by 9 publications

(8 citation statements)

References 10 publications

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“…The results showed no statistical differences in any of the parameters recorded (medial, distal, buccal, and lingual). Bone formation was comparable in both groups 140 . In a randomized controlled trial, DFDBA and Bio‐Oss covered with collagen membranes had positive effects on alveolar ridge preservation in extraction sockets.…”

Section: Applicationsmentioning

confidence: 79%

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Multiple biomaterials for immediate implant placement tissue repair: Current status and future perspectives

Su,

Jia,

Wang

et al. 2024

MedComm – Biomaterials and Applications

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Immediate oral implant placement is a widely accepted technique, known for its efficacy in reducing treatment duration, surgical visits, and overall healing time. One of the primary challenges associated with immediate implant placement is the attainment of initial stability. The inevitable loss of bone and soft tissue after extraction poses a risk to implant osseointegration in both vertical and horizontal dimensions. Guided tissue regeneration/guided bone regeneration (GTR/GBR) is a well‐established method for periodontal regeneration. However, current GTR/GBR membranes lack tissue inherent regeneration properties and necessitate combination with grafts to enhance tissue recovery. In this context, biomaterials have emerged as a promising option due to their good biocompatibility, biodegradability, and bioactive properties. They present a potential alternative to standard autologous/allograft procedures. The field of biomaterials for bone regeneration has rapidly evolved, developing new guiding materials and engineering techniques. These advances have become integral in addressing tissue defects at the immediate implant site. Various materials such as bioceramics, natural polymers, and synthetic polymers have been used for tissue repair. This article undertakes an etiological examination of tissue deficiency associated with immediate implant placement. Additionally, it reviews the advantages and disadvantages of a variety of biomaterials, aiming to provide references for clinical treatment and areas for further investigation.

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Section: Applicationsmentioning

confidence: 79%

“…Bone formation was comparable in both groups. 140 In a randomized controlled trial, DFDBA and Bio-Oss covered with collagen membranes had positive effects on alveolar ridge preservation in extraction sockets. Histomorphometrically, the percentage of new bone formation was higher in the DFDBA group than in the Bio-Oss group.…”

Section: Bone Tissuementioning

confidence: 99%

Multiple biomaterials for immediate implant placement tissue repair: Current status and future perspectives

Su,

Jia,

Wang

et al. 2024

MedComm – Biomaterials and Applications

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“…This property of BCP ceramic is attributed to the similarity of CDA ratios (essential for the formation of microcrystals) in ceramic to those of bone apatite crystals observed after implantation of MBCP [ 11 ]. The four paramount properties of osteoinduction, osseointegration, osteoconduction, and osteogenesis are incorporated in this bioceramic [ 25 , 37 , 43 - 46 ].…”

Section: Reviewmentioning

confidence: 99%

“…Another grafting technique known as xenograft is also being practiced, which could be bovine-derived, porcine-derived, or coralline calcium-derived [9,10]. Xenograft has osteoconductive properties with minimal limitation and no donor site morbidity [11][12][13]. However, due to it having no osteogenic and osteoinductive properties, the possibility of disease transmission and ethical problems bounds the use of this grafting technique in certain situations [5].…”

Section: Introductionmentioning

confidence: 99%

Bicalcium Phosphate as an Asset in Regenerative Therapy

Maheshwari,

Taori,

Bajaj

et al. 2023

Cureus

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After a loss of a tooth, alveolar bone resorption is immutable, leaving the area devoid of sufficient bone quality and mass for a successful and satisfactory implant or any other dental treatment. To treat this problem of irreversible bone loss, bone grafting is the primary solution and a well-accepted technique. The use of bone grafting procedures has increased in recent years. This review is about the various bone grafting techniques and best-situated material available currently along with their trump cards and limitations. In the thorough discussion regarding bone grafting materials and their substitutes, one alloplastic material has shown unbeaten and the most satisfactory properties than any other material, “bicalcium phosphate” (BCP). BCP is a mixture of hydroxyapatite (HA) and beta-tricalcium phosphate (B-TCP) usually obtained through sintering calcium-deficient apatite (CDA) at or above 700°C or by other methods such as hydrolysis or precipitation. The review also shows comparative studies done to understand the effect, most adequate balance, and impact of ratios of HA/B-TCP on the properties, structure, and success rate of this material. The objective of the review is to enlighten the principal characteristic of the most likely used bone graft material presently, i.e., BCP. The most impeccable characteristic of BCP is its capability to osteointegrate, which results in a superior interface. This interface depicts a dynamic process that includes physicochemical reactions, crystal-protein interactions, cell and tissue colonization, and bone remodeling. BCP has certain essential properties that could be put forth as its advantage over any other substitute. These properties include bioactivity, osteointegration, osteoinduction, osteogenesis, and biodegradation, which are mostly governed by modifying the HA/B-TCP ratio. Other applications of BCP are feasible, such as in drug administration and scaffolds for tissue engineering.

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“…To avoid complications, other bone substitutes are often used in medium and smallsize defects and include allografts (human bone other than the patient's own (e.g., extracted from cadavers)), xenografts (bone from animals other than human species), and synthetic materials with osteoconductive properties that can be reabsorbed by the body, releasing substances that contribute to the formation of new bone (e.g., ceramics, bioactive glasses, polymers, synthetic hydroxyapatite (HA)) [12,13].…”

Section: Introductionmentioning

confidence: 99%

Bone Grafts in Dental Medicine: An Overview of Autografts, Allografts and Synthetic Materials

Ferraz

2023

Materials

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This review provides an overview of various materials used in dentistry and oral and maxillofacial surgeries to replace or repair bone defects. The choice of material depends on factors such as tissue viability, size, shape, and defect volume. While small bone defects can regenerate naturally, extensive defects or loss or pathological fractures require surgical intervention and the use of substitute bones. Autologous bone, taken from the patient’s own body, is the gold standard for bone grafting but has drawbacks such as uncertain prognosis, surgery at the donor site, and limited availability. Other alternatives for medium and small-sized defects include allografts (from human donors), xenografts (from animals), and synthetic materials with osteoconductive properties. Allografts are carefully selected and processed human bone materials, while xenografts are derived from animals and possess similar chemical composition to human bone. Synthetic materials such as ceramics and bioactive glasses are used for small defects but may lack osteoinductivity and moldability. Calcium-phosphate-based ceramics, particularly hydroxyapatite, are extensively studied and commonly used due to their compositional similarity to natural bone. Additional components, such as growth factors, autogenous bone, and therapeutic elements, can be incorporated into synthetic or xenogeneic scaffolds to enhance their osteogenic properties. This review aims to provide a comprehensive analysis of grafting materials in dentistry, discussing their properties, advantages, and disadvantages. It also highlights the challenges of analyzing in vivo and clinical studies to select the most suitable option for specific situations.

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A Comparison of Xenograft Graft Material and Synthetic Bioactive Glass Allograft in Immediate Dental Implant Patients

Cited by 9 publications

References 10 publications

Multiple biomaterials for immediate implant placement tissue repair: Current status and future perspectives

Multiple biomaterials for immediate implant placement tissue repair: Current status and future perspectives

Bicalcium Phosphate as an Asset in Regenerative Therapy

Bone Grafts in Dental Medicine: An Overview of Autografts, Allografts and Synthetic Materials

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