A Comparitive Study between Vecuronium and Rocuronium for Intubating Condition and Hemodynamic Changes

Somani, M.; Vyas, Shantanu; Sharma, Poonam; Sachdev, Sudhir; Mathur, Vijay Prakash; Chaturvedi, Shashi; Vyas, C K

doi:10.9790/0853-13613339

Cited by 7 publications

(10 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There was significant increase in heart rate from baseline after 1 minute in rocuronium 0.6 mg/kg group than rocuronium 1mg/kg and succinylcholine 1 mg/kg group. These findings were similar to those observed by Misra M et al, [18] Bhale P et al, [19] Gupta et al, [20] Somani M et al [21] There was increase in systolic blood pressure by 7.7%, 10.9% and 8.1% from pre induction value following administration of succinylcholine 1 mg/kg body weight, rocuronium 0.6 mg/kg and 1 mg/kg body weight one minute following intubation, respectively. There was significant increase in systolic blood pressure from baseline after 1 minute in rocuronium 0.6 mg/kg group than in rocuronium 1 mg/kg and succinylcholine group.…”

Section: Cardiovascular Changessupporting

confidence: 82%

“…There was a similar increase in diastolic blood pressure by 7.7%, 11.8 % and 9.3% from pre induction value following administration of succinylcholine 1mg/kg body weight, rocuronium 0.6 mg/kg and 1 mg/kg body weight one minute following intubation, respectively. Similar findings were observed by Misra M et al, [18] Bhale P et al, [19] Gupta S et al [20] and Somani M et al [21] There was significant increase in diastolic blood pressure from baseline after 1 minutes in rocuronium 0.6 mg/kg group than rocuronium 1 mg/kg and succinylcholine 1 mg/kg group. Similar findings were observed by Misra M et al [18] and Somani M. [21] There was no significant difference seen in mean saturation of oxygen from baseline to post induction in the groups which is comparable to Marsch A.…”

Section: Cardiovascular Changessupporting

confidence: 79%

“…Similar findings were observed by Misra M et al, [18] Bhale P et al, [19] Gupta S et al [20] and Somani M et al [21] There was significant increase in diastolic blood pressure from baseline after 1 minutes in rocuronium 0.6 mg/kg group than rocuronium 1 mg/kg and succinylcholine 1 mg/kg group. Similar findings were observed by Misra M et al [18] and Somani M. [21] There was no significant difference seen in mean saturation of oxygen from baseline to post induction in the groups which is comparable to Marsch A. [22] …”

Section: Cardiovascular Changessupporting

confidence: 79%

See 2 more Smart Citations

Comparative Study of Succinylcholine with Different Doses of Rocuronium Bromide for Tracheal Intubation during General Anaesthesia

Panda¹,

Padhihari²,

Meitei³

et al. 2017

IOSR JDMS

View full text Add to dashboard Cite

Section: Cardiovascular Changessupporting

confidence: 82%

Section: Cardiovascular Changessupporting

confidence: 79%

Section: Cardiovascular Changessupporting

confidence: 79%

See 1 more Smart Citation

Comparative Study of Succinylcholine with Different Doses of Rocuronium Bromide for Tracheal Intubation during General Anaesthesia

Panda¹,

Padhihari²,

Meitei³

et al. 2017

IOSR JDMS

View full text Add to dashboard Cite

“…Similar findings were observed by Misra M. et al 7 and M. Somani, P. Sharma, S. Sachdev, V. Mathur, S. Chaturvedi. 14 There wasno significant difference seen in mean saturation of oxygen from baselineto pre induction, during induction, 1, 2 & 5 minutes after induction in both the groups (p value >1. 00) which is comparable to Marsch et al (2011).…”

Section: Figmentioning

confidence: 74%

“…These findings were similar to those observed by Misra M. et al, 7 PramodBhale, Narender Bhandari, SelvaKumaran P, Rashmee Joshi, 10 Shobhana Gupta and R. Kirubahar, 13 M. Somani, P. Sharma, S. Sachdev, V. Mathur, S. Chaturvedi. 14 The systolic blood pressure increased significantly after induction (maximum at 1 minute) with both Succinylcholine (133.22±13.85) and Rocuronium (130.40±14.59). There was significant increase in systolic blood pressure from baseline after 2 minute in Rocuronium group than in Succinylcholine group.…”

Section: Figmentioning

confidence: 91%

A COMPARATIVE CLINICAL EVALUATION OF INTUBATING CONDITIONS AND HAEMODYNAMIC EFFECTS AFTER ADMINISTRATION OF SUCCINYL CHOLINE & ROCURONIUM BROMIDE

Kumar¹,

Saran²,

Chandra³

et al. 2015

jemds

View full text Add to dashboard Cite

BACKGROUND: Rapid and safe endotracheal intubation is of paramount importance in practice of general anesthesia. Succinylcholine chloride, a depolarizing muscle relaxant due to its quick onset of action and excellent intubating conditions has remained a muscle relaxant of choice. Rocuronium was proved to be safe alternative to Succinylcholine for endotracheal intubation. AIMS: Study was conducted to evaluate & compare the onset time, clinical duration and intubating condition of Succinylcholine and Rocuronium Bromide and Haemodynamic changes caused by these agents. METHODS & MATERIALS:80 patients were randomly divided into two groups. Group-1, Succinylcholine (1. 5mg/kg) and group-2 Rocuronium Bromide (0.6mg/kg). After 60 sec of administration of muscle relaxant, intubating conditions were judged according to scoring system by Cooper et al. 1 Onset time and duration of action was noted. Hemodynamic parameters ( Heart rate, Systolic Blood Pressure, Diastolic Blood Pressure, Mean Atrial pressure and SPO2) were monitored before intubation, during intubation and just after intubation at 1, 2 and 5 minutes. RESULTS: The mean onset time and duration of action was significantly longer for Rocuronium (95.15±9.47 seconds) than Succinylcholine (59.80±14.30 seconds) and Rocuronium (42.60±13.15 minutes) than Succinylcholine (5.10±2.35 minutes). Intubating conditions was excellent in 35(87%) and good in 5(12.5%) patients in succinylcholine whereas, in Rocuronium produced excellent intubation in only 23(57.5%) patients and good intubation in 14(35%) patients. The heart rate increased significantly after induction (maximum at 1 minute) with both Rocuronium (98.75±15.53) and Succinylcholine (112.75±15.89). But it gradually declined towards normal and change in heart rate with either drug was not significant at 5 minutes. The mean blood pressure increased significantly after induction (maximum at 1 minute) with both Succinylcholine (100.52±8.11) and Rocuronium (100.61±7.83). But it gradually declined towards normal in 5 minutes after induction. CONCLUSION: Rocuronium bromide is a safe, haemodynamically stable and good alternative for Suxamethonium for endotracheal intubation and can be used for safe induction and intubation, if there is no prediction of difficult intubation.

show abstract

A Study of Hemodynamic Effects of Rocuronium Bromide and other Muscle Relaxants in Cardiac Surgery

Gupta¹,

Agarwal²

2020

IJCMR

View full text Add to dashboard Cite

Introduction: Use of muscle relaxants in cardiac surgery poses a challenge to anaesthesia due to narrow margin of safety and limited cardiovascular function. Therefore aim of present study is to find out the hemodynamic effects of Rocuronium bromide and other muscle relaxant in cardiac surgery. Material and Methods: Present study was carried out on sixty (60) patients of different age groups from both sexes scheduled for various cardiac surgical procedures at L.P.S. Institute of Cardiology, GSVM medical college Kanpur during the period of August 1998 to August 1999. Patients were classified in 3 equal groups. Muscle relaxants were given according to the group and hemodynamic parameters were recorded carefully at the interval of two, five and ten minutes. Results: No statistically significant changes were observed in systolic blood pressure, diastolic blood pressure and central venous pressure at 2 minutes, 5 minutes and 10 minutes after the administration of all three drugs (P >0.05) compared with control values. Significant increase in heart rate was observed at 2 minutes and 5 minutes after the administration of Pancuronium (P <0.05). Conclusion: On basis of present study's result, it can be said that Rocuronium bromide is safer in cardiac surgery as compared to Vecuronium & Pancuronium.

show abstract

A Comparitive Study between Vecuronium and Rocuronium for Intubating Condition and Hemodynamic Changes

Cited by 7 publications

References 19 publications

Comparative Study of Succinylcholine with Different Doses of Rocuronium Bromide for Tracheal Intubation during General Anaesthesia

Comparative Study of Succinylcholine with Different Doses of Rocuronium Bromide for Tracheal Intubation during General Anaesthesia

A COMPARATIVE CLINICAL EVALUATION OF INTUBATING CONDITIONS AND HAEMODYNAMIC EFFECTS AFTER ADMINISTRATION OF SUCCINYL CHOLINE & ROCURONIUM BROMIDE

A Study of Hemodynamic Effects of Rocuronium Bromide and other Muscle Relaxants in Cardiac Surgery

Contact Info

Product

Resources

About