Evaporative sprays are encountered in a wide range of engineering applications. Since clustering of droplets in sprays leads to strong inhomogeneity in the spatial distribution of droplet concentration which impacts mass, momentum, and energy exchange between the spray and the surrounding flow, a detailed investigation of droplet clustering in evaporating sprays is important. In the current research work, we experimentally investigate the spatial evolution of droplet cluster characteristics in an evaporating acetone spray injected from an air-assist atomizer. The droplet size and velocity are measured using Interferometric Laser Imaging for Droplet Sizing (ILIDS) technique. In detail characterization of the droplet clusters is achieved by application of Voronoi analysis to particle image velocimetry (PIV) images of the spray droplets. This approach not only identifies the droplet clusters but also provides area, length scale, and local droplet number density within the clusters. The identified droplet clusters are multi-scale and could be classified into either large- or small-scale clusters, which scale with spray half-width and Kolmogorov length scale, respectively. Experiments are also conducted in water spray under the same operating conditions. Despite the similarity in the droplet clustering process between the two sprays at small scales of air turbulence, some distinct trends are observed for the large-scale clusters in the acetone spray. This is attributed to the higher evaporation rate of acetone droplets which promotespreferential accumulation of droplets.