A composite material used as a membrane for ophthalmology applications

Stodolak, E.; Gumuła, T.; Leszczyński, Rafał; Wieczorek, J.; Błażewicz, S.

doi:10.1016/j.compscitech.2010.07.007

Cited by 13 publications

(2 citation statements)

References 15 publications

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“…Composite materials are widely used in heat transfer and thermal management of equipment, such as aerospace [1][2][3], braking and friction systems [4,5], fins, tanks, heat exchangers [6][7][8][9], electrical applications [10,11] and biomaterials [12,13]. The effective thermal conductivity is one of the main thermo-physical properties used to quantify the thermal behavior of these heterogeneous materials.…”

Section: Introductionmentioning

confidence: 99%

Analytical Study of Thermal Heat Conduction inside Two Orthotropic Mediums in Cylindrical Geometry

Nikchi¹,

Zniber²,

Hamza³

et al. 2021

World Congress on Mechanical, Chemical, and Material Engineering

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The present work focuses on the two-dimensional steady-state thermal behavior of two orthotropic mediums in a coaxial cylindrical geometry. The whole lateral surface is subjected to a flux density while the end sections are maintained at prescribed temperatures. The resolution of the problem is carried out analytically by the variable separation technique, taking into account the boundary conditions and the continuity of temperatures and flux at the interface between the two mediums. The resolution in dimensionless form, expressed in terms of the Bessel functions, made it possible to identify the parameters of the study, namely the ratio of the main thermal conductivities for each medium as well as the ratio of the radial thermal conductivities of the two mediums. A numerical code was developed, in order to simulate the effect of the study parameters on heat transfer within the two mediums, in terms of isotherms.

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Section: Introductionmentioning

confidence: 99%

Analytical Study of Thermal Heat Conduction inside Two Orthotropic Mediums in Cylindrical Geometry

Nikchi¹,

Zniber²,

Hamza³

et al. 2021

World Congress on Mechanical, Chemical, and Material Engineering

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“…A new generation of membrane materials can play role in other processes in living organism i.e. control of inter eye pressure (ophthalmology application) and creation of optimal conditions of tissue regeneration (membrane in GTR technique or GNR technique) [4][5][6]. The most popular membranes used for bone tissue regeneration are applied in dentistry and periodontology [7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Resorbable Polymer Membranes for Medical Applications

Stodolak-Zych

Łuszcz

Menaszek

et al. 2014

JBBTE

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A bioresorbable polymer poly-ε-caprolactone (PCL) was tested in order to obtain porous materials suitable for membranes. The commercial PCL with various molecular weights (2kDa, 60kDa, 80 kDa) but similar polydispersity has been chosen. The membranes were produced by the casting method and the membrane materials underwent microstructure investigation (SEM) to assess the size of pores and an average porosity of the membranes. The membranes permeability was established by means of ultrafiltration. Also wettabilility and basic mechanical properties (such as: tensile strength Rm, Youngs modulus, E) were established. The membranes durability was tested in in vitro conditions (PBS/37°C) by monitoring of changes by means of ion conductivity measurement and changes in the molecular weight (the Ubbelohde method). The porous materials were tested towards biocompatibility, i.e. the membrane was contacted with the osteoblast line of NHOst cells (viability test, cells morphology). Non-perforated PCL foil was used as a reference material. The best physicochemical, mechanical and biological properties of the membranes were observed in case of application of PCL with molecular weight of 60 kDa.

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Evaluation of the use of fibrin and microcrystalline chitosan membranes as carriers for transforming growth factor beta‐1

Michalska

Kaplińska

Mirowski

et al. 2012

J of Applied Polymer Sci

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The aim of this study was to describe the mechanical features of homogeneous and layered chitosan (Ch) and fibrin–chitosan (Fb–Ch) membranes as well the kinetics of transforming growth factor beta‐1 (TGF‐β1) release from five types of polymer carriers. Composites in the form of a film containing physiologically clotted fibrin (Fb) and microcrystalline chitosan (MCCh) were prepared and then crosslinked with calcium chloride. The films were characterized by Infrared (IR) spectroscopy, mechanical tests (film thickness, maximal tensile force, breaking strength, and elongation at break), and SEM images. The results reveal that Ch film demonstrates higher efficiency in binding TGF‐β1 and, at the same time, is less effective in its release—1.25% of the total amount between 6 h and 14 days. However, the Fb membrane binds TGF‐β1 not as strongly, which leads to more effective release of the compound—25% after 6 h and 28.98% of the total amount after 14 days. The factor TGF‐β1 is released in vitro from Fb–Ch membranes with different kinetics. The most efficient release of TGF‐β1 was observed in the case of the layered Fb–Ch (M4 L) membrane (after 14 days it reached a maximal value of 14.08% of the total amount). The release was lower with increasing Ch concentrations in the film, suggesting a high affinity of TGF‐β1 with the Fb–Ch component. The Fb–Ch membrane with incorporated TGF‐β1 may prove to be a very useful scaffold in the tissue regeneration process. This study demonstrates that Fb and MCCh gels could be used as carrier matrices for the controlled release of bioactive TGF‐β1. It was found that the degree of TGF‐β1 release from the membrane is influenced by the physiochemical and mechanical characteristics of the films and by its affinity to growth factor TGF‐β1. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013

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A composite material used as a membrane for ophthalmology applications

Cited by 13 publications

References 15 publications

Analytical Study of Thermal Heat Conduction inside Two Orthotropic Mediums in Cylindrical Geometry

Analytical Study of Thermal Heat Conduction inside Two Orthotropic Mediums in Cylindrical Geometry

Resorbable Polymer Membranes for Medical Applications

Evaluation of the use of fibrin and microcrystalline chitosan membranes as carriers for transforming growth factor beta‐1

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