A Comprehensive Analysis of Histopathologic Examination Results of Tonsillectomy Specimens

Kayabaşı, Serkan; Hızlı, Ömer; Cayir, Serkan; Ordu, Melike

doi:10.7759/cureus.6655

Cited by 3 publications

(2 citation statements)

References 22 publications

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“…Primary tuberculosis of tonsils in the absence of pulmonary involvement is a rare entity with an incidence of <5%, although our literature review identified more cases of primary tonsillar tuberculosis than secondary forms (59% vs 41%): primary tonsillar tuberculosis was found in 59% of patients, 39.4% of them presenting tonsils as unique tuberculosis site [3,10,[12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31] while the rest of 9.6% of them had simultaneous tuberculosis and epithelial squamous cell carcinoma of the tonsil-1 case, [32] 4 cases of tuberculosis of tonsil and adenoids, [2,[30][31][32][33][34][35] 3 cases of tonsillar and pharyngeal tuberculosis, [9,20,36] 1 case of tonsillar and cervical lymphadenitis related to tuberculosis, [25] 2 cases of tuberculosis involving the tonsils, cervical and mesenteric lymphadenitis, [9,37] and 1 case of tonsillar tuberculosis developed under anti-TNF alfa inhibitors and Methotrexate treatment. [38] The percentage of patients with concomitant pulmonary involvement was 41, [10,16,[39][40]…”

Section: Discussionmentioning

confidence: 99%

Primary tonsillar tuberculosis in a pediatric patient

Moisă¹,

Miron²,

Adam-Raileanu³

et al. 2021

Medicine

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Rationale:Tuberculosis is an entity that usually affects the lungs, although extrapulmonary sites can also be involved. Tonsils are rarely affected, especially in the absence of pulmonary disease, primary tonsillar tuberculosis being a diagnostic challenge for the clinician.Patient concerns:We present the case of a 14-year-old female teenager, presented to our Pediatric Service with a 14-day history of dysphagia, odynophagia and left reflex otalgia associated with a 5 kg weight loss. Clinical examination revealed mild pharyngeal erythema, marked enlargement of the left tonsil infiltrating the lateral pharyngeal wall and the uvula and painful, mobile, nonadherent to deep bilateral latero-cervical adenopathy.Diagnosis:Positive interferon-gamma release assay (QuantiFERON-TB gold). Mantoux test reading was 16 mm.Interventions:During hospitalization, the patient received Clindamycin and Gentamicin for 3 days i.v., with discrete relief of symptoms and inflammatory markers. On the 4th day of hospitalization, treatment with Imipenem/Cilastin is started for 7 days in micro-perfusion, with tonsil hypertrophy decrease in size and favorable clinical evolution.Outcome:Tonsil hypertrophy decreased in size and patient had a favorable clinical evolution. At discharge, the patient was given a 6-month course of anti-tuberculous drug.Lessons:The particularity of this case is represented by the rarity of primary tuberculosis of tonsils in children, with unilateral involvement, displaying at the same time a common issue encountered in the current practice: the limitations and the difficult course of setting the diagnosis due to the involvement of relatives in the medical act.

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Section: Discussionmentioning

confidence: 99%

Primary tonsillar tuberculosis in a pediatric patient

Moisă¹,

Miron²,

Adam-Raileanu³

et al. 2021

Medicine

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“…10 Pada 484 pasien (411 anak dan 73 dewasa) dengan hipertrofi tonsil dilakukan pemeriksaan histopatologi dan ditemukan 20,4% inflamasi kronik, 45,24% reaktif hiperplasia limfoid, 28,3% kronik inflamasi dan reaktif hiperplasia limfoid, 0,61% malignansi, 4,45% aktinomikosis, 0,2% tuberkulosis, 0,61% papilloma skuamosa dan 0,61% kista inklusi epidermal. 11 Walaupun adenoma pleomorfik adalah tumor jinak, tumor tersebut dapat mengalami rekurensi dan diferensiasi menjadi karsinoma. Pada penelitian Danish Nationwide study of Incidence, terdapat 2,86% rekurensi adenoma pleomorfik dari 5,497 pasien.…”

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Adenoma Pleomorfik di Tonsil: Kasus Langka

Pelealu,

Hamida

2023

ejki

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Adenoma pleomorfik adalah gambaran tumor jinak secara histopatologis yang dapat ditemukan di kelenjar liur, kelenjar parotis, kelenjar submandibular, kelenjar palatina minor dan kelenjar bukal minor. Pada makalah ini dilaporkan kasus adenoma pleomorfik di tonsil pada perempuan berusia 38 tahun dengan keluhan rasa tersumbat di tenggorok sejak 1 tahun lalu. Pasien sulit menelan tanpa disertai rasa nyeri saat menelan. Demam, batuk, flu, keluar darah dari telinga, hidung, mulut dan gangguan pendengaran disangkal. Pada pemeriksaan orofaring didapatkan T4/T3, hingga menutupi uvula. Pada pemeriksaan leher, tidak tampak pembesaran dan pada saat palpasi leher tidak teraba pembesaran kelenjar getah bening. Dilakukan biopsi jaringan di tonsil dengan hasil adenoma pleomorfik dan tidak ada keganasan sehingga dilakukan tonsilektomi pada kedua tonsil. Pengangkatan kedua tonsil diharapkan dapat mencegah rekurensi dan diferensiasi ke arah keganasan. Dengan laporan kasus ini diharapkan kewaspadaan dokter pada pembesaran tonsil.

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Surgeon Preference on Sending Routine Tonsillectomy Specimens for Pathological Evaluation

et al. 2022

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Introduction Despite the presence of a growing body of literature suggesting cost-ineffectiveness of routine pathologic analysis of tonsillectomy specimens, little is known about common institutional policies and practice patterns of pediatric otolaryngologists. The objectives of this study were to determine the prevalence of routine pathological evaluation of tonsillectomy specimens for uncomplicated pediatric adenotonsillectomy procedures and to evaluate opinions regarding this controversy among board-certified pediatric otolaryngologists. Methods This was a cross-sectional survey study sent to board-certified pediatric otolaryngologists currently practicing and registered with the American Society of Pediatric Otolaryngology (ASPO) assessing their institutions’ or practices’ current policies on sending routine tonsillectomy specimens for pathology, their experience with this practice, and their opinions on whether routine pathologic analysis should be employed. Basic statistical analysis was then conducted. Results Respondents mostly practiced in an academic setting (68.4%), with the next most common being academically affiliated private practice (21.8%), and private practice was the least common (9.8%). Most respondents (85.1%) did not agree with routine pathologic analysis of otherwise uncomplicated pediatric tonsillectomy specimens. Conclusion Most pediatric otolaryngologists who responded to this survey do not support routine pathological analysis of otherwise uncomplicated pediatric tonsillectomy specimens. However, the results are likely biased and should be interpreted carefully, since only a small percentage of pediatric otolaryngologists responded to the survey. Potential cost savings could be seen by patients, payers, and hospital systems with judicious use of surgical pathology, specifically in cases with concurrent signs or symptoms suspicious for malignancy.

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A Comprehensive Analysis of Histopathologic Examination Results of Tonsillectomy Specimens

Cited by 3 publications

References 22 publications

Primary tonsillar tuberculosis in a pediatric patient

Primary tonsillar tuberculosis in a pediatric patient

Adenoma Pleomorfik di Tonsil: Kasus Langka

Surgeon Preference on Sending Routine Tonsillectomy Specimens for Pathological Evaluation

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