Carbonate reservoirs have significant reserves globally, but the substantial heterogeneity brings intractable difficulties to exploration. In the work area, the thick salt rock reduces the resolution of pre-salt seismic signals and increases the difficulty of reservoir characterization. Therefore, this paper proposes to utilize wavelet frequency decomposition technology to depict the seismic blank reflection area’s signal and improve the pre-salt signal’s resolution. The high-precision pre-stack inversion based on Bayesian theory makes full use of information from various angles and simultaneously inverts multiple elastic parameters, effectively depicting reservoirs with substantial heterogeneity. Integrating the high-precision inversion results and the Kuster-Toksöz model, a porosity prediction method is proposed. The inversion results are consistent with the drilling rock samples and well-logging porosity results. Moreover, the reef’s accumulation and growth, which conform to the geological information, proves the accuracy of the above methods. This paper also discusses the seismic reflection characteristics of reefs and the influence of different lithological reservoirs on the seismic waveform response characteristics through forward modeling, which better proves the rationality of porosity inversion results. It provides a new set of ideas for future pre-salt carbonate reef reservoirs’ prediction and characterization methods.