A comprehensive characterization of culturable endophytic bacteria of Paris polyphylla and their potential role in microalgal growth in co-culture

Sonowal, Shashanka; Ahmed, Refad; Chikkaputtaiah, Channakeshavaiah; Basar, Egam; Velmurugan, Natarajan

doi:10.1016/j.apsoil.2022.104410

Cited by 11 publications

(3 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, the development of -omics-based techniques such as metagenomics analysis has been shown to be useful for preliminary screening for bioactive compounds in environmental samples and the current microbial profile, facilitating the bioprospecting of promising metabolites [115,116]. Sonowal et al (2022) employed a genomic approach for annotation of secondary metabolites in endophytic bacteria associated with the endangered Himalayan medicinal plant Paris polyphylla, revealing the presence of siderophores and antimicrobial lipopeptides encoding genes which are considered relevant against pathogen attack [117]. This also led to the identification of several bioactive compounds evidenced by the occurrence of nonribosomal peptides (NRPS) and polyketide synthases (PKS).…”

Section: -Omics-based Research and Standardized Methodologies As Futu...mentioning

confidence: 99%

“…Based on this genomics context the authors evaluate the co-culture of these endophytes with the microalgae Micractinium sp. GA001, showing a positive modulation of the microalgal photosynthesis and an increased accumulation of lipids [117]. To our knowledge, neither high throughput assays nor culture independent -omics screenings have been used for microalgae co-cultures directly, yet they represent promising techniques to preliminary studies regarding microorganisms' compatibility for co-cultivation.…”

Section: -Omics-based Research and Standardized Methodologies As Futu...mentioning

confidence: 99%

See 1 more Smart Citation

Insights into Co-Cultivation of Photosynthetic Microorganisms for Novel Molecule Discovery and Enhanced Production of Specialized Metabolites

Rojas-Villalta,

Gómez-Espinoza,

Murillo-Vega

et al. 2023

Fermentation

View full text Add to dashboard Cite

Meso- and extremophilic microalgae and cyanobacteria have a wide range of biotechnological applications. However, the industrial demand for bioactive molecules and the redundancy of these molecules has resulted in a need for new methodologies for enhanced production and the discovery of specialized metabolites. Co-cultivation has been established as a promising approach to addressing these challenges. In this context, this work aimed to describe the state of the art of the co-cultivation method involving meso- and extremophilic photosynthetic microorganisms, as well as discuss the advantages, challenges, and limitations of this approach. Co-culture is defined as an ecology-driven method in which various symbiotic interactions involving cyanobacteria and microalgae can be used to explore new compounds and enhanced production. Promising results regarding new bioactive metabolite expression and increased production through co-cultivation-based research support that idea. Also, the metabolic diversity and evolutionary adaptations of photosynthetic microorganisms to thrive in extreme environments could improve the efficiency of co-cultivation by allowing the implementation of these microorganisms. However, the complexity of ecological interactions and lack of standardization for co-cultivation protocols are obstacles to its success and scientific validation. Further research in symbiotic interplays using -omics and genetic engineering, and predictive experimental designs for co-cultures are needed to overcome these limitations.

show abstract

Section: -Omics-based Research and Standardized Methodologies As Futu...mentioning

confidence: 99%

Section: -Omics-based Research and Standardized Methodologies As Futu...mentioning

confidence: 99%

Insights into Co-Cultivation of Photosynthetic Microorganisms for Novel Molecule Discovery and Enhanced Production of Specialized Metabolites

Rojas-Villalta,

Gómez-Espinoza,

Murillo-Vega

et al. 2023

Fermentation

View full text Add to dashboard Cite

show abstract

“…In the past studies, the authors have reviewed the population density, trade, cultivation and propagation, chemical and biological perspectives, pharmacological uses and efects, reproductive biology, genetic diversity, and management of P. polyphylla [5,6,26,27], and there has been no systematic study to understand multiple attributes together. Despite the fact that only a small number of authors have reviewed the bioactive compounds [5], traditional uses [6,28], microbiological aspects [29], distribution, ethnobotanical uses, molecular characterization, and species cultivation [6], there is a dearth of knowledge regarding the distribution of medicinal plants, their suitability for diferent habitats, the ratio of demand to supply, and the efects of climate change. Moreover, attributes like ecology, biotechnology, molecular biology, and conservation have yet to be reviewed.…”

Section: Introductionmentioning

confidence: 99%

Traditional Uses, Active Ingredients, and Biological Activities of Paris polyphylla Smith: A Comprehensive Review of an Important Himalayan Medicinal Plant

Rawat

Pandey

Rawat

et al. 2023

Journal of Chemistry

View full text Add to dashboard Cite

Paris polyphylla Smith (family: Melanthiaceae), a high-value medicinal herb endemic to the Himalayan region, has drawn much attention recently due to its immense use in the traditional healthcare system since ancient times. In the present review, an extensive database on P. polyphylla was systematically searched from databases such as Medline/PubMed, Scopus, the Web of Science, and the online service E-library.ru and SCImago (https://www.scimagojr.com/). Information on species, ecology, distribution, trade, ethnopharmacology, pharmacology, biotechnology, and molecular biology was gathered from 1979 to 2023 using 116 research publications. Major steroidal saponins such as Paris saponin I, V, VI, VII, and H have been found substantially effective in anticancer activity, abnormal uterine bleeding, dysfunctional uterine bleeding, and menorrhagia. Traditional breeding and propagation techniques cannot keep up with the world’s growing demand for herbal drugs. Therefore, it is critically necessary to take conservation measures and develop novel techniques for growing and cultivating this economically significant and highly valuable therapeutic herb. The advanced biotechnological approaches like micropropagation and genetic analysis introduced long back are either rare or lacking in the case of P. polyphylla. It contains a wealth of information that will serve as a baseline data source for various stakeholders, researchers working on various research aspects, and policymakers to define appropriate utilization and conservation plans for a high-value commercial medicinal plant called P. polyphylla. The review provides an updated overview and critical assessment of secondary data regarding the past and recent applications and interventions of P. polyphylla.

show abstract

Analysis of antimicrobial biological activity of a marine Bacillus velezensis NDB

Wang,

Zhang,

Wang

et al. 2024

Arch Microbiol

View full text Add to dashboard Cite

A comprehensive characterization of culturable endophytic bacteria of Paris polyphylla and their potential role in microalgal growth in co-culture

Cited by 11 publications

References 46 publications

Insights into Co-Cultivation of Photosynthetic Microorganisms for Novel Molecule Discovery and Enhanced Production of Specialized Metabolites

Insights into Co-Cultivation of Photosynthetic Microorganisms for Novel Molecule Discovery and Enhanced Production of Specialized Metabolites

Traditional Uses, Active Ingredients, and Biological Activities of Paris polyphylla Smith: A Comprehensive Review of an Important Himalayan Medicinal Plant

Analysis of antimicrobial biological activity of a marine Bacillus velezensis NDB

Contact Info

Product

Resources

About