This PhD dissertation is the result of a three-year research project at the Department of Materials and Production at Aalborg University in close collaboration with Vestas Wind Systems A/S. The project is motivated by an industrial need and research deficit of methods and models for the financial evaluation of reconfigurable manufacturing systems in global production networks.The research project aims to support decision-making to advance a paradigm shift in the production domain that can enable efficient adaptability and resilience to uncertain changes. These capabilities are needed to secure a competitive advantage in the global wind energy industry. The fierce competition amongst firms increases the introduction rate of larger wind turbines for the onshore and offshore markets. Like the markets, the production is global across multiple factories and countries. Supply disruptions, transportation restrictions, and localization requirements pressure the firms to produce near the demand. However, the demand fluctuates on variety, volume, timing, and location, requiring the production mix of the factories to be adapted accordingly. This imposes frequent reinvestments in capital-intensive assets, which is further intensified when using dedicated manufacturing systems.ix ACKNOWLEDGMENTS I never believed I would complete a PhD project. I never even intended for university. Somehow, I find myself in this position. It required hard work, some luck, and, most of all, support from the people around me. I could not have done it without them.Firstly, I would like to thank my three supervisors, Thomas Ditlev Brunø, Ann-Louise Andersen, and Kjeld Nielsen. Without your support, advice, and guidance, I could not have managed the project. Ann-Louise, thank you for your encouragement to continue the PhD when I lacked belief. Thomas and Ann-Louise, thank you for forcing me to take a break when the pressure overwhelmed me. I would also like to thank Rasmus Andersen and Alessia Napoleone for the discussions and advice. A special thanks to my colleagues from Jönköping, Sweeden. Carin Rösiö, thank you for the opportunity to visit. Simon Boldt and Filip Skärin, thank you for our collaboration and friendship.Secondly, I would like to thank Vestas Wind Systems A/S, Manufacturing Academy of Denmark, and Innovation Fund Denmark for allowing me to conduct the research. My first industrial supervisor, Bjørn Christensen, thank you for opening the doors to Vestas and for your guidance. My second industrial supervisor, Mads Bejlegaard, thank you for picking me up, seeing my potential, and supporting my development. Michael Kofoed Dam, thank you for the warm welcome to the team and our field trips. Daniel Grud Hellerup Sørensen, thank you for the collaboration and advice. A special thanks to Henrik Espensen and Søren Damgaard for guiding me through the corporate maze and helping my work reach new heights up the corporate ladder.Last but not least, I would like to thank my family. The love of my life and fiancé, Aja Katrine Konnerup, thank you fo...