2024
DOI: 10.7759/cureus.74907
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A Comprehensive Pan-Cancer Analysis Reveals GRB7 as a Potential Diagnostic and Prognostic Biomarker

Areig M Attaelmanan,
Shyma Alzubair,
Abdalla S Ahmmed
et al.

Abstract: Background and aim: Growth factor receptor-bound protein 7 (GRB7) belongs to a group of adaptor proteins characterized by their conserved multidomain structure. These proteins are involved in cellular signaling pathways that regulate cell growth, proliferation, and differentiation. Alterations in GRB7 expression have been linked to multiple human cancers. However, its role as a diagnostic and prognostic marker remains underexplored. This study aimed to assess the diagnostic and prognostic relevance of GRB7 in … Show more

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