A 19-day-old Japanese male infant presented with a 12-day history of fevers and facial rash. He was born by spontaneous vaginal delivery at 36 weeks' gestational age with a birthweight of 3048 g (6.7 lb) with Apgar scores of 9 and 10. There were no complications during the prenatal and perinatal periods. His mother had no history of ringworm infection, positive IgG antibodies against rubella virus and herpes zoster virus, and serology findings negative for human immunodeficiency virus, hepatitis B virus, and syphilis. His family history was unremarkable.On examination, he had a temperature of 38.0°C, a heart rate of 150/min, and a respiratory rate of 60/min. Slightly scaly annular erythematous plaques with central atrophy and raised margins were present on the forehead and periorbital areas (Figure). The remainder of the physical examination was unremarkable. Laboratory investigation showed a whitebloodcellcountof10.5×10 3 /μL(referencerange,4.8-18.5×10 3 /μL); hemoglobin level, 7.2 g/dL (8.7-13.5 g/dL); platelet count, 47 × 10 4 /μL (28-91 ×10 4 /μL); aspartate aminotransferase level, 23 IU/L (20-62 IU/L); alanine aminotransferase level, 9 IU/L (11-45 IU/L); serum creatinine level, 0.27 mg/dL (0.12-0.27 mg/dL); uric acid level, 2.6 mg/dL (1.8-5.3 mg/dL); and C-reactive protein level, 6.94 mg/dL (<0.30 mg/dL). Figure. Scattered annular erythematous plaques with central atrophy and raised margin on the forehead and periorbital areas of patient. WHAT WOULD YOU DO NEXT? A. Provide education on proper facial cleansing and moisturizing B. Administer topical antifungals C. Order antinuclear antibody, anti-Ro/SS-A, and anti-La/SS-B antibody testing for both the infant and his mother D. Order a serologic test for syphilis for the infant Clinical Review & Education