A comprehensive review on nettle effect and efficacy profiles, Part I: Herba urticae

Chrubasik, J.; Roufogalis, Basil D.; Wagner, Hildebert; Chrubasik, Sigrun

doi:10.1016/j.phymed.2007.03.004

Cited by 71 publications

(67 citation statements)

References 48 publications

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“…Two authors (CC and SC) extracted the data independently and evaluated the quality of the studies and the strength of the evidence of clinical effectiveness using the same criteria as in previous reviews , Gagnier et al, 2004, Chrubasik et al, 2006, 2007a,b, 2008, Vlachojannis et al, 2009, 2010a.…”

Section: Methodsmentioning

confidence: 99%

The clinical effectiveness of chokeberry: a systematic review

Chrubasik

2010

Phytotherapy Research

132

101

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Products derived from the black chokeberry, Aronia melanocarpa, are claimed to be beneficial in disorders or diseases associated with oxidative stress. The claims are based on evidence from in vitro studies and animal experiments. The active principle – a mixture of procyanidins, anthocyanins and phenolic acids – constitutes one of the most potent natural antioxidants. A systematic review was carried out of the quality of the clinical trials on chokeberry products that had been published up to December 2009, and conventionally established criteria were used to assess the strength of the evidence for their clinical effectiveness. Thirteen studies were identified. The quality of most of the trials and, correspondingly, the evidence of effectiveness for Aronia products is poor. Though laboratory and clinical data indicate that chokeberry products may well be useful as ‘functional food’ for disorders or diseases related to oxidative stress, these promising indications need to be confirmed in more rigorous studies before putative therapeutic uses can be confidently recommended for chokeberry products. Copyright © 2010 John Wiley & Sons, Ltd.

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Section: Methodsmentioning

confidence: 99%

The clinical effectiveness of chokeberry: a systematic review

Chrubasik

2010

Phytotherapy Research

132

101

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“…Across Europe and other countries it is also used for the treatment of gout, dropsy, rheumatism and for weight loss. Nettle roots are commonly used in hair products to treat eczema and dandruff along with helping to stimulate hair growth (Fern, 1997;Bnouham et al, 2003;Gulcin et al, 2004;Chrubasika et al, 2007).…”

Section: Introductionmentioning

confidence: 99%

Changes in the productivity of wild and cultivated stinging nettle (Urtica dioica L.) as influenced by the planting density and crop age

Jankauskienė

Gruzdevienė

2015

Zemdirbyste-Agriculture

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An interest in the stinging nettle (Urtica dioica L.), as a multi-purpose plant, has been on the increase in many countries throughout Europe and even worldwide recently. The study was conducted at the Upytė Experimental Station of the Lithuanian Research Centre for Agriculture and Forestry in 2010-2012 in which we investigated the productivity of the stinging nettle crop, established at different planting densities and that of nettle crops of different age (the number of cropping years), as well as changes in yielding and morphological parameters in senescent plants. Some data of cultivated nettle were compared to those of wild nettle. The research findings showed that in all experimental years, irrespective of crop age, the productivity per plant was higher at a planting density of 60 × 100 cm. The green biomass yield generally was higher in the treatments planted at 60 × 60 cm density. The mean green above-ground mass yield per plant was going down with crop senescence. The mean absolutely dry above-ground mass yield was higher in 2010 (close to 14 t ha -1 ), while in 2011 and 2012, the yield was much lower -6.5-7.1 t ha -1 . The green above-ground mass yield of wild nettle was lower than that of cultivated nettle and the absolutely dry above-ground mass yield of wild nettle was approximately 2-3 times lower than that of cultivated nettle. The mean crop density (at harvest) increased over the years of investigation and was higher in an older crop. Starting from the 3 rd cropping year, crop density at harvest in the treatment planted at lower density (60 × 100 cm) exceeded crop density at the treatments planted at higher density (60 × 60 cm). The number of wild nettle stems per m 2 was much lower than that of cultivated nettle. The greatest increase (110-217%) in the crop density over the vegetation period was found in the plots planted at lower density (60 × 100 cm). In an older crop, stinging nettle produced more but shorter stems.

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“…Polysaccharides isolated from this fraction stimulated T lymphocyte proliferation and influenced the complement system. Ethanol root extract has been investigated and showed potent human leukocyte elastase (HLE, an enzyme released by polymorphonuclear granulocytes that mediates the inflammatory process) suppressive activity [17,18,24].…”

Section: Discussionmentioning

confidence: 99%

“…UD has been reported to be effective for arthritis, neuralgia, allergic rhinitis, and diabetes. Traditionally, it has been used for gout, hair loss, and mild bleeding [15][16][17][18].…”

Section: Introductionmentioning

confidence: 99%