A comprehensive review on Rasam: A South Indian traditional functional food

Devarajan, Agilandeswari; MohanMarugaRaja, Muthu Kumaradoss

doi:10.4103/phrev.phrev_13_17

Cited by 26 publications

(15 citation statements)

References 65 publications

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“…In Ayurveda external environment like Jala, Vayu, Bhumi and Kala has been explained in relation to health and disease. 18 The purification methods mentioned in Ayurveda for water, air and soil are may be crude and useful in domestic level in rural area still have scientific basis , these can be propagated through mass media to reach even in urban area.…”

Section: Environmental Hygienementioning

confidence: 99%

Preventive strategies to combat infections–a review of traditional practices and Ayurveda concepts

Mn¹

2020

IJCAM

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India is the land of traditions and religious beliefs that stand proudly next to the global technology. The great sages of India chanted shantih mantra and its echoes have reverberated through centuries. The quest for happiness and success has been the dynamic factor in the course of evolutionary history. It is reflected in Brihadaranyaka Upanishad, which conveys that "May all be free from illness/ disease" which speaks about Universal health. Ayurveda advocates several non-pharmacological measures that are critical to overall health, including diet, sleep, mental factors, and environmental hygiene. There is a need to decode some of the non pharmacological, prophylactic measures that might sound superstitious to many, but are age-old practices of our ancestors and widely followed. This paper highlights prophylaxis aspects practiced traditionally in different parts of India along with Ayurvedic views and rationale behind these practices. Many age-old practices widely followed by our ancestors to prevent infectious diseases like daily regimens, seasonal regimens, personal hygiene, environmental hygiene, dietary guidelines, immunity boosting measures are relevant even today.

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Section: Environmental Hygienementioning

confidence: 99%

Preventive strategies to combat infections–a review of traditional practices and Ayurveda concepts

Mn¹

2020

IJCAM

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“…It remains to be critically examined whether these have been deliberately composed with an appreciation of therapeutic properties of spices and herbs, or are accidentally emerged constructs. Spices are frequently used as part of functional foods, for example, the Indian dish rasam is a concoction of different spices and has been reported to be hypoglycemic, anti-anemic and antipyretic [ 49 ]. Sambar , another predominantly spice-based recipe has been shown to work against prostrate cancer [ 50 ].…”

Section: Discussionmentioning

confidence: 99%

Data-driven analysis of biomedical literature suggests broad-spectrum benefits of culinary herbs and spices

et al. 2018

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Spices and herbs are key dietary ingredients used across cultures worldwide. Beyond their use as flavoring and coloring agents, the popularity of these aromatic plant products in culinary preparations has been attributed to their antimicrobial properties. Last few decades have witnessed an exponential growth of biomedical literature investigating the impact of spices and herbs on health, presenting an opportunity to mine for patterns from empirical evidence. Systematic investigation of empirical evidence to enumerate the health consequences of culinary herbs and spices can provide valuable insights into their therapeutic utility. We implemented a text mining protocol to assess the health impact of spices by assimilating, both, their positive and negative effects. We conclude that spices show broad-spectrum benevolence across a range of disease categories in contrast to negative effects that are comparatively narrow-spectrum. We also implement a strategy for disease-specific culinary recommendations of spices based on their therapeutic tradeoff against adverse effects. Further by integrating spice-phytochemical-disease associations, we identify bioactive spice phytochemicals potentially involved in their therapeutic effects. Our study provides a systems perspective on health effects of culinary spices and herbs with applications for dietary recommendations as well as identification of phytochemicals potentially involved in underlying molecular mechanisms.

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“…"Rasam" is a famous South Indian spicy soup that has been made fresh every day and served with rice 20 . Tamarind, red pepper, black pepper, cumin seed, fenugreek, asafoetida, garlic, tomato, coriander, curry leaves, sesame oil, and mustard are the main avors (spices) of rasam 21 . These spices used to make rasam, a "functional food" include a plethora of bioactive chemicals that have been linked to improved tumor prognosis 22 .…”

Section: Introductionmentioning

confidence: 99%

Graph Theoretical Network Analysis and Pharmacoinformatics-Based Investigation of Bioactive Compounds of Rasam (South Indian Recipe) Against Human Cancer

Kalimuthu¹,

Panneerselvam²,

Pavadai³

et al. 2021

Preprint

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Spice-rich recipes are referred to as "functional foods" because they include a variety of bioactive chemicals that have health-promoting properties in addition to their nutritional value. Using pharmacoinformatics-based analysis, we explored the relevance of bioactive chemicals found in rasam (a south Indian cuisine) against oxidative stress-induced human malignancies. The rasam is composed of twelve main ingredients, each of which contains a variety of bioactive chemicals. Sixty-six bioactive compounds were found from these ingredients, and their structures were downloaded from Pubchem. To find the right target via graph theoretical analysis (mitogen-activated protein kinase (MAPK)) and display their signaling route, a network was built. Among the identified compounds sixty-six bioactive compounds were used for in silico molecular docking study against MAPK, the top four compounds were chosen for further study based on their docking score and binding affinities. In silico predicted ADMET characteristics of the titled compounds were used to assess their drug-likeness. Molecular dynamics (MD) simulation modelling methodology were also used to analyze the effectiveness and safety profile of top four selected bioactive chemicals based on the docking score, as well as to assess the stability of the MAPK-ligand complex structure. Surprisingly, the discovered docking scores against MAPK revealed that the titled bioactive chemicals distribution varied between -3.5 and -10.6 kcal/mol. MD simulation validated the stability of four chemicals at the MAPK binding pockets, including Assafoetidinol A (ASA), Naringin (NAR), Rutin (RUT), and Tomatine (TOM). According to the results obtained, fifty of the sixty-six compounds showed higher binding affinity (-6.1 to -10.6 kcal/mol), and four of these compounds may be used as lead compounds to protect cells against oxidative stress-induced human malignancies.

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A comprehensive review on Rasam: A South Indian traditional functional food

Cited by 26 publications

References 65 publications

Preventive strategies to combat infections–a review of traditional practices and Ayurveda concepts

Preventive strategies to combat infections–a review of traditional practices and Ayurveda concepts

Data-driven analysis of biomedical literature suggests broad-spectrum benefits of culinary herbs and spices

Graph Theoretical Network Analysis and Pharmacoinformatics-Based Investigation of Bioactive Compounds of Rasam (South Indian Recipe) Against Human Cancer

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