A comprehensive review on recent advances in preparation, physicochemical characterization, and bioengineering applications of biopolymers

Das, Abinash; Ringu, Togam; Ghosh, Sampad; Pramanik, Nabakumar

doi:10.1007/s00289-022-04443-4

Cited by 148 publications

(67 citation statements)

References 198 publications

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“…Biopolymers can be classified into natural, originating from living organisms, or synthetic biopolymers, manufactured chemically from bio-sourced monomers. 22 Synthetic biopolymers can be biodegradable e.g. poly(ε-caprolactone) (PCL) and poly(lactic acid) (PLA) or they can be non-biodegradable e.g.…”

Section: Cellulose: Structure and Propertiesmentioning

confidence: 99%

Utilizing cellulose-based conducting hydrogels in iontronics

2023

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Section: Cellulose: Structure and Propertiesmentioning

confidence: 99%

Utilizing cellulose-based conducting hydrogels in iontronics

2023

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“…Polycondensation enables the development of specialized polymers, including phosphorus-containing polymers, melamine/formaldehyde microspheres, and flexible foam and fiber resins, finding use in pharmaceuticals and tissue engineering. Synthetic biopolymers, with their distinct characteristics and versatile synthesis methods, play a pivotal role in various industries, from medicine to environmental protection …”

Section: Synthesis and Properties Of Bioengineered Polymersmentioning

confidence: 99%

“…Synthetic biopolymers, with their distinct characteristics and versatile synthesis methods, play a pivotal role in various industries, from medicine to environmental protection. 14 Poly(D,L-lactic acid) (PDLLA) was synthesized using D,Lacid and SnCl 2 as a catalyst through melt polycondensation, with a resulting Mη of 4100 Da. PDLLA was used for drug delivery, producing effective microspheres for lung targeting with good in vitro and in vivo performance for erythromycin and ciprofloxacin with a sustained release profile.…”

Section: Bioengineered Polymersmentioning

confidence: 99%

Applications of Bioengineered Polymer in the Field of Nano-Based Drug Delivery

Mishra,

Shah,

Patel

et al. 2023

ACS Omega

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The most favored route of drug administration is oral administration; however, several factors, including poor solubility, low bioavailability, and degradation, in the severe gastrointestinal environment frequently compromise the effectiveness of drugs taken orally. Bioengineered polymers have been developed to overcome these difficulties and enhance the delivery of therapeutic agents. Polymeric nanoparticles, including carbon dots, fullerenes, and quantum dots, have emerged as crucial components in this context. They provide a novel way to deliver various therapeutic materials, including proteins, vaccine antigens, and medications, precisely to the locations where they are supposed to have an effect. The promise of this integrated strategy, which combines nanoparticles with bioengineered polymers, is to address the drawbacks of conventional oral medication delivery such as poor solubility, low bioavailability, and early degradation. In recent years, we have seen substantially increased interest in bioengineered polymers because of their distinctive qualities, such as biocompatibility, biodegradability, and flexible physicochemical characteristics. The different bioengineered polymers, such as chitosan, alginate, and poly(lactic-co-glycolic acid), can shield medications or antigens from degradation in unfavorable conditions and aid in the administration of drugs orally through mucosal delivery with lower cytotoxicity, thus used in targeted drug delivery. Future research in this area should focus on optimizing the physicochemical properties of these polymers to improve their performance as drug delivery carriers.

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“…Several classification criteria have been used for biopolymers, considering their origin, chemical structure, and properties, and also their industrial applications. Polymers directly extracted from biomasses (e.g., polysaccharides, proteins), polymers typically produced from bio-derived monomer (polylactic acid; PLA), and polymers synthesized by microorganisms (e.g., polyhydroxyalkanoates; PHAs) are of high interest nowadays, in terms of production, potential application, and biodegradability [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Biopolymers Produced by Lactic Acid Bacteria: Characterization and Food Application

et al. 2023

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Plants, animals, bacteria, and food waste are subjects of intensive research, as they are biological sources for the production of biopolymers. The topic links to global challenges related to the extended life cycle of products, and circular economy objectives. A severe and well-known threat to the environment, the non-biodegradability of plastics obliges different stakeholders to find legislative and technical solutions for producing valuable polymers which are biodegradable and also exhibit better characteristics for packaging products. Microorganisms are recognized nowadays as exciting sources for the production of biopolymers with applications in the food industry, package production, and several other fields. Ubiquitous organisms, lactic acid bacteria (LAB) are well studied for the production of exopolysaccharides (EPS), but much less as producers of polylactic acid (PLA) and polyhydroxyalkanoates (PHAs). Based on their good biodegradability feature, as well as the possibility to be obtained from cheap biomass, PLA and PHAs polymers currently receive increased attention from both research and industry. The present review aims to provide an overview of LAB strains’ characteristics that render them candidates for the biosynthesis of EPS, PLA, and PHAs, respectively. Further, the biopolymers’ features are described in correlation with their application in different food industry fields and for food packaging. Having in view that the production costs of the polymers constitute their major drawback, alternative solutions of biosynthesis in economic terms are discussed.

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A comprehensive review on recent advances in preparation, physicochemical characterization, and bioengineering applications of biopolymers

Cited by 148 publications

References 198 publications

Utilizing cellulose-based conducting hydrogels in iontronics

Utilizing cellulose-based conducting hydrogels in iontronics

Applications of Bioengineered Polymer in the Field of Nano-Based Drug Delivery

Biopolymers Produced by Lactic Acid Bacteria: Characterization and Food Application

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