A comprehensive review on the utility of resonance Rayleigh scattering in pharmaceutical analysis; with emphasis on nanostructure role in analyte probing

Integrated resonance Rayleigh scattering approach utilizing Box–Behnken experimental design for the facile quantification of prucalopride in pharmaceutical tablets and human urine with sustainability assessment

“…These associates attain significant enhancement in the RRS intensity which could be measured and exploited for the analysis of the target analytes. 17 …”

“…The analytical strategy based on Resonance Rayleigh Scattering (RRS) is gaining prominence due to its combination of high sensitivity and simplicity, making it an essential analytical approach. This technique has been applied in the analysis of various chemical and therapeutically active agents, 17 a diverse range of biological macromolecules, such as nucleic acids 18 and proteins, 19 in addition trace metal ions. 20 …”

“…A variety of chemical dyes and pigments were employed as probes in the development of RRS approaches. 17 These dyes have either acidic or basic nature, and some of them have highly conjugated system with rigid structures that naturally emit light. At the optimal pH, the dye is ionized, then complexed with the analyte.…”

“…The observed phenomenon has the potential to be utilized for the determination of very low concentration of the desired analyte down to a few nano-grams. 17 …”

Validated spectrofluorimetric and resonance Rayleigh scattering methods for determining naftidrofuryl in varied pharmaceutical samples based on its interaction with erythrosin B

“…Recently, xanthene dyes (eosin Y, erythrosin B, fluorescein, merbromin) have been used as colorimetric, fluorescent, and/or RRS analytical reagents for determining a wide range of active pharmaceutical ingredients [12]. For example, eosin Y and merbromin dyes have been reported for determining daclatasvir, cyclobenzaprine, fluvoxamine, atomoxetine, oxybutynin, dexlansoprazole and some β-blockers [13][14][15][16][17][18][19], while erythrosin B has been utilized for determining rupatadine, duloxetine, terbinafine, venlafaxine, nilotinib trospium, and varenicline [20][21][22][23][24][25][26].…”