A comprehensive review on the ethno-medicinal and pharmacological properties of Terminalia chebula fruit

Cardiovascular Disease (CVD) is one of the most prevalent diseases in the world, comprising a variety of disorders such as hypertension, heart attacks, Peripheral Vascular Disease (PVD), dyslipidemias, strokes, coronary heart disease, and cardiomyopathies. The World Health Organization (WHO) predicts that 22.2 million people will die from CVD in 2030. Conventional treatments for CVDs are often quite expensive and also have several side effects. This potentiates the use of medicinal plants, which are still a viable alternative therapy for a number of diseases, including CVD. Natural products' cardio-protective effects result from their anti-oxidative, anti-hypercholesterolemia, anti-ischemic, and platelet aggregation-inhibiting properties. The conventional therapies used to treat CVD have the potential to be explored in light of the recent increase in the popularity of natural goods and alternative medicine. Some natural products with potential in the management of cardiovascular diseases such as Allium sativum L., Ginkgo biloba, Cinchona ledgeriana, Ginseng, Commiphoramukul Digitalis lanata, Digitalis purpurea L. Murrayakoenigii, Glycyrrhiza glabra, Polygonum cuspidatum, Fenugreek, Capsicum annum, etc. are discussed in this article.

show abstract

Traditional Medicine and Modern Drug Delivery Systems: Promising Roles of PhytoNanotechnology in Rheumatoid Arthritis Treatment

Ilhan,

Ozturk

2024

Herbal Medicine for Autoimmune Diseases

View full text Add to dashboard Cite

Phyto-nanotechnology presents a promising avenue for revolutionizing rheumatoid arthritis (RA) treatment. By integrating plant-derived compounds with nanotechnology, this approach addresses the limitations of conventional RA therapies. Nanoformulations of phytochemicals, such as curcumin, resveratrol, and quercetin, enable targeted drug delivery to inflamed joints, optimizing therapeutic efficacy while minimizing systemic side effects. Enhanced bioavailability, attributed to the encapsulation of phytochemicals within nanoparticles, facilitates improved pharmacokinetics and delivery across biological barriers. The immunomodulatory and anti-inflammatory properties of phytochemicals are harnessed more effectively through nanoparticle-mediated sustained release, offering the potential to suppress inflammatory processes and mitigate joint damage. Furthermore, the cartilageprotective and regenerative capabilities of certain plant-derived compounds can be optimized with nanotechnology, promoting joint health. The versatility of phytonanotechnology allows for combination therapies, synergizing the benefits of multiple compounds and conventional drugs within nanoparticles. While these advancements hold substantial promise, further research is imperative to refine nanoparticle formulations, assess safety, and validate efficacy through preclinical and clinical studies, ultimately paving the way for transformative RA treatments in clinical practice. In this chapter, phyto-nano drug delivery systems that can increase the effectiveness of medicinal plants in RA treatment are focused on.

show abstract

A comprehensive review on the ethno-medicinal and pharmacological properties of Terminalia chebula fruit

Cited by 4 publications

References 117 publications

Unveiling the genetic potential of Terminalia chebula Retz. accessions from North-East and South India: A morphometric analysis

Unveiling the genetic potential of Terminalia chebula Retz. accessions from North-East and South India: A morphometric analysis

The Potential of Natural Products in the Management of Cardiovascular Disease

Traditional Medicine and Modern Drug Delivery Systems: Promising Roles of PhytoNanotechnology in Rheumatoid Arthritis Treatment

Contact Info

Product

Resources

About