A computational tool for accelerated analysis of oligomeric proanthocyanidins in plants

Zhang, Mengliang; Sun, Jianghao; Chen, Pei

doi:10.1016/j.jfca.2016.11.014

Cited by 10 publications

(14 citation statements)

References 39 publications

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“…Other than xanthones, mangosteen pericarp is also known to contain one of the highest procyanidin content, compared to other fruit such as cranberry, Fuji apple, jujube, and litchi (Zhang, Sun & Chen, 2017c). These procyanidins include monomer (47.7%), dimer (24.1%), and trimer (26%) may also contribute to the anti-oxidant capability of mangosteen extract as shown in 1,1-diphenyl-2-picrylhydrazyl (DPPH) and Ferric Reducing Antioxidant Power (FRAP) assays (Qin et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

Recent updates on metabolite composition and medicinal benefits of mangosteen plant

Aizat¹,

Jamil²,

Ahmad-Hashim³

et al. 2019

PeerJ

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Background Mangosteen (Garcinia mangostana L.) fruit has a unique sweet-sour taste and rich in beneficial compounds such as xanthones. Mangosteen has been originally used in various folk medicines to treat diarrhea, wound, and fever. More recently, it has been used as a major component in health supplement products for weight loss and promoting general health. This is perhaps due to its known medicinal benefits including as anti-oxidant and anti-inflammation. Interestingly, the publications related to mangosteen has surged in recent years suggesting its popularity and usefulness in research laboratories. However, there is still no updated reviews (up to 2018) in this booming research area, particularly on its metabolite composition and medicinal benefits. Method In this review, we have covered recent articles within the year of 2016 to 2018, which focuses on several aspects including the latest findings on compound composition from mangosteen fruit as well as its medicinal usages. Result Mangosteen has been vastly used in medicinal areas including as anti-cancer, anti-microbial, and anti-diabetes treatments. Furthermore, we have also described the benefits of mangosteen extract in protecting various human organs such as liver, skin, joint, eye, neuron, bowel, and cardiovascular tissues against disorders and diseases. Conclusion All in all, this review describes the numerous manipulations of mangosteen extracted compounds in medicinal areas and highlights the current trend of its research. This will be important for future directed research and may allow researchers to tackle the next big challenge in mangosteen study; drug development and human applications.

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Section: Introductionmentioning

confidence: 99%

Recent updates on metabolite composition and medicinal benefits of mangosteen plant

Aizat¹,

Jamil²,

Ahmad-Hashim³

et al. 2019

PeerJ

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“…PCA is an unsupervised multivariate technique that models the variation in a data set with orthogonal vectors or principal components (PC) representing the maximum amount of variance . PPMC is a statistical method used to measure the similarity or association between two vectors (e.g., mass spectra, chromatograms). , The correlation coefficient ( r ) can be calculated as where x and y represent the relative intensity of each ion in two mass spectra and x̅ and y̅ are the average intensity of ions for each mass spectrum. The larger the correlation coefficient, the more similar the two mass spectra.…”

Section: Methodsmentioning

confidence: 99%

“…15 PPMC is a statistical method used to measure the similarity or association between two vectors (e.g., mass spectra, chromatograms). 16,17 The correlation coefficient (r) can be calculated as…”

Section: ■ Materials and Methodsmentioning

confidence: 99%

Forensic Fiber Analysis by Thermal Desorption/Pyrolysis-Direct Analysis in Real Time-Mass Spectrometry

et al. 2019

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The thermal desorption/pyrolysis-direct analysis in real time-mass spectrometry (TD/Py-DART-MS) method was developed for the analysis of fibers in this study. The fiber samples were pyrolyzed with a temperature gradient and the pyrolysis products were determined by DART-MS. The pyrogram from the TD/Py-DART-MS fiber analysis was found to be associated with the physical properties such as the melting points. At the same time, the TD/Py-DART-MS allows the analyst to obtain the chemical information such as polymeric backbone structures and dyes on the fiber. The pyrolysis profiles of common polymeric fibers in textile materials such as cotton, cellulose triacetate (CT), poly(caprolactam) (nylon-6), poly(hexamethylene adipamide) (nylon-6/6), poly(acrylonitrile) (PAN), poly(ethylene terephthalate) (PET), poly(butylene terephthalate) (PBT), poly(propylene) (PP), and polytrimethylene terephthalate (PTT) and their respective characteristic mass spectra were reported in this study. The fibers from 40 commercial textile samples were analyzed by the TD/Py-DART-MS method, and the statistical methods including principal component analysis (PCA) and Pearson product moment correlation (PPMC) were applied to classify and associate the fibers based on their mass spectral data. The strong correlation between the reference fiber mass spectral profiles and tested fiber mass spectral profiles was observed by using the PPMC method, and the identification accuracy was 97.5%. When combined, the mass spectral and pyrogram data, the types of fibers including the blended fibers were identified effectively. The TD/Py-DART-MS method also demonstrated the promising capability for the identification of dyes on fibers. Overall, the TD/Py-DART-MS method requires small sample size and minimal sample preparation but offers reproducible and multidimensional information for the fiber evidence rapidly (i.e., ∼6.7 min). Since the proposed method is simple to perform and the data are easy to interpret, this approach may significantly contribute to the fiber identification and comparison procedures in forensic settings with high sample throughput potential.

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“…Other than xanthones, mangosteen pericarp is also known to contain one of the highest procyanidin content, compared to other fruit such as cranberry, Fuji apple, jujube and litchi (Zhang et al 2017c). These procyanidins include monomer (47.7%), dimer (24.1%) and trimer (26%) may also contribute to the anti-oxidant capability of mangosteen extract as shown in DPPH and FRAP assays (Qin et al 2017).…”

Section: Metabolite Composition Of Mangosteenmentioning

confidence: 99%

Peer Review #2 of "Recent updates on metabolite composition and medicinal benefits of mangosteen plant (v0.2)"

2019

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Background. Mangosteen (Garcinia mangostana L.) fruit has unique sweet-sour taste and rich in beneficial compounds such as xanthones. Mangosteen has been originally used in various folk medicines to treat diarrhea, wound and fever. More recently, it has been used as a major component in health supplement products for weight loss and promoting general health. This is perhaps due to its known medicinal benefits including as anti-oxidant and anti-inflammation. Interestingly, the publications related to mangosteen has surged in recent years suggesting its popularity and usefulness in research laboratories. However, there is still no updated reviews (up to 2018) in this booming research area, particularly on its metabolite composition and medicinal benefits. Method. In this review, we have covered recent articles within the year of 2016 to 2018, which focuses on several aspects including the latest findings on compound composition from mangosteen fruit as well as its medicinal usages. Result. Mangosteen has been vastly used in medicinal area including as anti-cancer, anti-microbial and anti-diabetes treatments. Furthermore, we have also described the benefits of mangosteen extract in protecting various human organs such as liver, skin, joint, eye, neuron, bowel and cardiovascular tissues against disorders and diseases. Conclusion. All in all, this review describes the numerous manipulations of mangosteen extracted compounds in medicinal areas and highlights the current trend of its research. This will be important for future directed research and may allow researchers to tackle the next big challenge in mangosteen study; drug development and human applications.

show abstract

A computational tool for accelerated analysis of oligomeric proanthocyanidins in plants

Cited by 10 publications

References 39 publications

Recent updates on metabolite composition and medicinal benefits of mangosteen plant

Recent updates on metabolite composition and medicinal benefits of mangosteen plant

Forensic Fiber Analysis by Thermal Desorption/Pyrolysis-Direct Analysis in Real Time-Mass Spectrometry

Peer Review #2 of "Recent updates on metabolite composition and medicinal benefits of mangosteen plant (v0.2)"

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