A computer program package for relative survival analysis

Hakulinen, Timo; Abeywickrama, Kamal

doi:10.1016/0010-468x(85)90011-x

Cited by 330 publications

(146 citation statements)

References 7 publications

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“…Relative survival and 95% confidence intervals (CIs) were calculated as a measure of disease-specific survival (Hakulinen and Abeywickrama, 1985). The relative survival is the ratio between crude and expected survival and is close to disease-specific survival.…”

Section: Discussionmentioning

confidence: 99%

Incidence and survival rate of women with cervical cancer in the Greater Amsterdam area

et al. 2003

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To evaluate the effect of population-based cervical cancer screening on the occurrence of cervical cancer in The Netherlands, we investigated the incidence and survival of cervical cancer registered by a cancer registry in the Greater Amsterdam area. The incidence rate of squamous cell carcinoma decreased significantly from 9.2/100 000 women in 1988 to 5.9/100 000 in 2000 (Po0.001). The incidence rate of adenocarcinomas remained stable. After adjustment for age, stage and lymph node involvement, the relative risk of death was 1.6 times higher for patients with adenocarcinomas than for patients with squamous cell carcinoma (95% CI 1.2 -2.1). The decreased survival was related to histological type, as the effect remained significant after correction for confounding factors. Over time, the prognosis of women with squamous cell carcinoma improved significantly. No significant change was observed for women diagnosed with adenocarcinoma. These results suggest that the screening programme in The Netherlands as executed in the Greater Amsterdam area is associated with a decreased incidence and increased survival of patients with squamous cell carcinoma, but fails to detect (pre)malignant lesions of adenocarcinoma. Since more than 92% of adenocarcinomas and its precursors contain high-risk HPV, adding HPV testing to cytologic screening might improve the present screening programme in detecting adenocarcinoma and its precursor lesions.

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Section: Discussionmentioning

confidence: 99%

Incidence and survival rate of women with cervical cancer in the Greater Amsterdam area

et al. 2003

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“…Hence, relative survival was also estimated and compared for different groups. 18 Nation-specific mortality data were used for calculating expected survival.…”

Section: Methodsmentioning

confidence: 99%

Incidence and survival of squamous cell carcinoma of the tongue in Scandinavia, with special reference to young adults

Annertz

Anderson

Biörklund

et al. 2002

Intl Journal of Cancer

222

129

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In several countries, increased incidence of squamous cell carcinoma (SCC) of the tongue in young adults has been suspected during the last decades. Some reports indicate a lower survival rate for young patients compared to older patients. In other reports, there has not been any considerable difference in survival when comparing young adults to older patients, whereas some authors have shown better survival for young adults. This disease is rare in young adults, and early reports were based on comparable small numbers and selected patients. Our aim was first to perform a population-based study to determine if an increased incidence in SCC of the tongue could be verified in a larger population comprising the Scandinavian countries Denmark, Finland, Sweden and Norway. A second aim was to determine survival rates for young adults compared to older patients. The material was based on the annual cancer incidence and survival reports from the Scandinavian cancer registries. The study period was 1960 -1994. During that period, 5,024 SCCs of the tongue were reported. Of these, 276 (5.5%) were young adults (20 -39 years). The incidence increased at all ages except for women 65-79 years old. The increase was most pronounced in young adults: 0.06 -0.32 for men and 0.03-0.19 for women, counted by 100,000 person-years. Relative survival was significantly better for young adults compared to older patients.

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“…Relative survival (5-year) was calculated by the Hakulinen method (Hakulinen, 1982;Hakulinen and Abeywickrama, 1985) with 95% confidence intervals (CI) calculated from the standard error according to Greenwood's (1926) method. Relative survival is an estimate of the probability of cancer survival after adjusting for competing causes of death determined from general population life tables for women, specific for each country or registry.…”

Section: Methodsmentioning

confidence: 99%

Prognostic value of morphology and hormone receptor status in breast cancer – a population-based study

et al. 2004

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We analysed the 5-year relative survival among 4473 breast cancer cases diagnosed in 1990 -1992 from cancer registries in Estonia, France, Italy, Spain, the Netherlands and the UK. Among eight categories based on ICD-O codes (infiltrating ductal carcinoma, lobular plus mixed carcinoma, comedocarcinoma, 'special types', medullary carcinoma, not otherwise specified (NOS) carcinoma, other carcinoma and cancer without microscopic confirmation), the 5-year relative survival ranged from 66% (95% CI 61 -71) for NOS carcinoma to 95% (95% CI 90 -100) for special types (tubular, apocrine, cribriform, papillary, mucinous and signet ring cell); 27% (95% CI 18 -36) for cases without microscopic confirmation. Differences in 5-year relative survival by tumor morphology and hormone receptor status were modelled using a multiple regression approach based on generalised linear models. Morphology and hormone receptor status were confirmed as significant survival predictors in this population-based study, even after adjusting for age and stage at diagnosis.

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A computer program package for relative survival analysis

Cited by 330 publications

References 7 publications

Incidence and survival rate of women with cervical cancer in the Greater Amsterdam area

Incidence and survival rate of women with cervical cancer in the Greater Amsterdam area

Incidence and survival of squamous cell carcinoma of the tongue in Scandinavia, with special reference to young adults

Prognostic value of morphology and hormone receptor status in breast cancer – a population-based study

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