This chapter explores the transformative potential of disruptive innovations in non-profit governance. As technology and societal changes advance, non-profits must adapt to remain relevant and efficient. The discourse examines blockchain technology, artificial intelligence (AI), decentralized autonomous organizations (DAOs), gamification, and advanced financial models. Blockchain enhances financial transparency with an immutable ledger, boosting donor confidence. AI offers superior data analytics to understand donor behavior, optimize resources, and predict fundraising trends. DAOs use blockchain-based smart contracts for participative governance, empowering stakeholders. Gamification engages stakeholders by incorporating game elements, appealing to a tech-savvy audience. Advanced financial models like impact investing and social finance attract capital seeking both financial returns and social impact. Integrating these trends can improve transparency, stakeholder engagement, and financial robustness, ensuring sustainability and promoting societal progress.