At present, the society is in the era of high-quality development of knowledge and talents. In order to promote the efficiency growth and sustainable development strategy of enterprises, enterprises must establish and improve the talent management framework. This study mainly addresses the impact of professional skills development, incentive programs, and employee collaboration on the talent management framework. This paper surveyed 404 respondents from four private universities in Guangdong province, China. The survey was conducted as a questionnaire to obtain a quantitative data analysis. The description statistics and scale analysis of the data using SPSS software revealed the correlation between organizational talent management innovation and development and employee expertise, employee incentive Programs, and employee collaboration. The results showed significant associations between the three variables and the talent management framework. In order to improve the work performance of employees, it is necessary to strengthen the innovation and development of human resources, so as to establish a high-quality teacher team.