Let F be a totally real number field and E/F a totally imaginary quadratic extension of F . Let Π be a cohomological, conjugate self-dual cuspidal automorphic representation of GL n (A E ). Under a certain non-vanishing condition we relate the residue and the value of the Asai L-functions at s = 1 with rational structures obtained from the cohomologies in top and bottom degrees via the Whittaker coefficient map. This generalizes a result in Eric Urban's thesis when n = 2, as well as a result of the first two named authors, both in the case F = Q.