A conscious minimally invasive approach to remove follicular cysts and infundibular keratinizing acanthomas in five dogs

Loek, Rachael; Gardiner, David; Laporte, Carine

doi:10.1111/vde.13119

Cited by 2 publications

(1 citation statement)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The evidence suggests that specific HPV types play a co-factor role in the pathogenesis of skin cancer, potentially through mechanisms involving the suppression of DNA repair and the promotion of oncogenic transformation in the context of UV-induced DNA damage. Despite these associations, the exact causative role of HPV in skin cancer development remains to be fully elucidated, and further research is warranted to understand the complex interplay between HPV infection, immune response, UV exposure, and skin carcinogenesis [33,69]. The potential protective role of HPV vaccination against NMSC also requires additional investigation to determine its efficacy and feasibility as a preventive or adjuvant treatment strategy.…”

Section: Discussionmentioning

confidence: 99%

Human Papillomavirus-Associated Giant Clear Cell Acanthoma and Squamous Cell Carcinoma: A Rare Case Report and Literature Review

Cuomo,

Rozen,

Pentangelo

et al. 2024

JCM

View full text Add to dashboard Cite

Clear cell acanthoma (CCA) and squamous cell carcinoma (SCC) represent distinct entities within dermatological oncology, each posing unique diagnostic and therapeutic challenges. CCA is a rare, benign epidermal growth, often not associated with human papillomavirus (HPV) infection, whereas SCC, a more aggressive form of skin cancer, has been linked to both ultraviolet (UV) exposure and HPV. Understanding the co-occurrence of these conditions in a single patient can enhance diagnostic accuracy and therapeutic outcomes. We report a 64-year-old male who underwent an operation for a verruciform lesion in the right groin, which was diagnosed as HPV-positive CCA alongside keratinised SCC. A literature search across January 2024 revealed limited evidence directly linking HPV to CCA, suggesting a need for further investigation. The speculative association between HPV and CCA warrants deeper exploration, especially considering the potential for HPV to contribute to lesion development through indirect mechanisms. The coexistence of CCA and SCC in an elderly patient presents a unique clinical scenario. This emphasises the need for vigilant diagnosis and tailored treatment strategies, highlighting the gap in understanding the pathogenesis of CCA, particularly its potential association with HPV. Further research is crucial for elucidating the complex interactions governing these conditions and for developing targeted interventions.

show abstract

Section: Discussionmentioning

confidence: 99%