A Contemporary Appraisal on Impending Industrial and Agricultural Applications of Thermophilic-Recombinant Chitinolytic Enzymes from Microbial Sources

Akram, Fatima; Jabbar, Zuriat; Aqeel, Amna; Haq, Ikram Ul; Tariq, Shahbaz; Malik, Kausar

doi:10.1007/s12033-022-00486-0

Cited by 2 publications

(1 citation statement)

References 159 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Chitinase enhances bioremediation at contaminated sites by breaking down chitin-rich pollutants into less toxic compounds, aiding microbial degradation (Akram et al 2022b), which reduces harmful substances in soil and water, promoting environmental health. Chitin-based materials might absorb heavy metals harmful to ecosystems and health, which might be difficult to detect and remove; here, chitinase, being participatory in heavy metal resistance could degrade metal-bound chitin, releasing metals for easy access and removal.…”

Section: Environmental Remediationmentioning

confidence: 99%

Chitinases: expanding the boundaries of knowledge beyond routinized chitin degradation.

Unuofin,

Odeniyi,

Majengbasan

et al. 2024

Environ Sci Pollut Res

View full text Add to dashboard Cite

Chitinases, enzymes that degrade chitin, have long been studied for their role in various biological processes. They play crucial roles in the moulting process of invertebrates, the digestion of chitinous food, and defense against chitin-bearing pathogens. Additionally, chitinases are involved in physiological functions in crustaceans, such as chitinous food digestion, moulting, and stress response. Moreover, chitinases are universally distributed in organisms from viruses to mammals and have diverse functions including tissue degradation and remodeling, nutrition uptake, pathogen invasion, and immune response regulation. The discovery of these diverse functions expands our understanding of the biological significance and potential applications of chitinases. However, recent research has shown that chitinases possess several other functions beyond just chitin degradation. Their potential as biopesticides, therapeutic agents, and tools for bioremediation underscores their significance in addressing global challenges. More importantly, we noted that they may be applied as bioweapons if ethical regulations regarding production, engineering and application are overlooked.

show abstract

Section: Environmental Remediationmentioning

confidence: 99%