A controlled study of anxiety and morbid cognitions at initial screening for Human Immunodeficiency Virus (HIV) in a cohort of people with haemophilia

Jones, Q.J.; Garsia, Roger; Wu, Richard; Job, R. F. Soames; Dunn, Stewart M.

doi:10.1016/0022-3999(94)00147-2

Cited by 7 publications

(4 citation statements)

References 34 publications

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“…Catalan et al demonstrated that haemophiliacs infected with HIV are more likely to show evidence of psychological morbidity than are their seronegative counterparts; however, the levels of psychologic morbidity are generally low [ 13]. Several researchers have already described the psychological effects of HIV on haemophiliacs [ 11–14]. In this study, dissatisfaction with social security and pension was a specific feature of the HIV‐positive haemophiliacs, and may derive from the origin of HIV infection, i.e.…”

Section: Discussionmentioning

confidence: 70%

“…The clinical severity of haemophilia affects personality characteristics, leading to the avoidance of hazardous activities [ 24]. In addition, HIV infection causes haemophiliacs to have psychological problems [ 13–15], and problems in daily life [ 5]. The QOL of those infected with HIV has been assessed by many researchers [ 25–27].…”

Section: Discussionmentioning

confidence: 99%

“…Although psychiatric problems in haemophiliacs with HIV infection have been reported [ 11–15], studies of HIV‐related disability in rehabilitation medicine are either small or anecdotal [ 16]. Physical functional disabilities and the satisfaction in daily life [ 17] of HIV‐positive haemophiliacs have also not been studied sufficiently.…”

Section: Introductionmentioning

confidence: 99%

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Health status and satisfaction of asymptomatic HIV‐positive haemophiliacs in Kyushu, Japan

et al. 1999

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The purpose of this study was to elucidate the effects of human immunodeficiency virus (HIV) on haemophiliacs with physical functional disabilities induced by haemophilia in Kyushu, Japan. The subjects were 38 adult haemophiliacs who were selected from 129 patients registered with the North Kyushu Haemophilia Centre. They were divided into 21 asymptomatic HIV-positive and 17 HIV-negative adult haemophiliacs. Coagulation factor levels, modified DePalma classification, Arthritis Impact Measurement Scale 2 (AIMS 2), and a satisfaction in daily life (SDL) questionnaire were used to investigate the clinical severity of their haemophilia and arthropathy, physical functional disabilities, and satisfaction. Although there were no significant differences in the objective assessments of health status between the HIV-positive and -negative haemophiliacs, the HIV-positive haemophiliacs were significantly more dissatisfied with their social activities and mood, according to AIMS 2, and with social intercourse, job, self-development, and social security and pension according to SDL assessment. These dissatisfactions were due to the effects of HIV, in addition to the physical functional disabilities that were caused by haemophilia. Dissatisfaction with social security and pension may be a specific feature in HIV-positive haemophiliacs in Japan resulting from the origin of HIV infection.

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Section: Discussionmentioning

confidence: 70%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Health status and satisfaction of asymptomatic HIV‐positive haemophiliacs in Kyushu, Japan

et al. 1999

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“…Jones and colleagues focus on HIV infection and argue that there is a possible risk factor for the appearance of psychological symptoms, even before noticeable physical signs. [36][37][38][39][40] The psychological dynamics in HIV-positive PWH were analyzed over the years by considering only parameters such as stress and the relationship between infections. Specifically considering HIV and mental suffering, the association is still confused even now that vaccinations and antiretroviral therapies slow the progression of the disease.…”

Section: Resultsmentioning

confidence: 99%

Health Related Quality of Life and Psychopathological Symptoms in People With Hemophilia, Bloodborne Co-Infections and Comorbidities: An Italian Multicenter Observational Study

Schiavoni

Pruneti

Guidotti

et al. 2023

Mediterr J Hematol Infect Dis

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Background: The health-related quality of life (HRQoL) of people with hemophilia (PWH) is an important issue, especially considering people suffering from chronic diseases beyond hemophilia. The principal aim of this study was to investigate the presence and relevance of psychological symptoms, both internalizing and externalizing, lifestyle, and HRQoL in a group of Italian PWH with chronic bloodborne co-infections and comorbidities. Furthermore, the research describes the association between psychological aspects and the impact of disease-related characteristics (type of hemophilia, presence of co-infections, and comorbidities) on them. Methods: Seventy patients (mean age 46.77±11.3), 64 with severe hemophilia A (Factor VIII: C < 1 IU/dL) and 6 with severe hemophilia B (Factor IX <1 IU/dL), were consecutively recruited from seven Hemophilia Centers in Italy of Italian Association of Hemophilia Centers (AICE). In order to assess psychological symptoms, HRQoL, and lifestyle, three psychological questionnaires were administered (the SCL-90-R, SF-36, and PSQ, respectively). Results: A general decline in the quality of life and an increase in the tendency to adopt a lifestyle characterized by hyperactivity emerged. Inverse correlations were found between HRQoL and psychological distress. Although the SCL-90-R did not reveal symptoms above the clinical cut-off, co-infections significantly increased anxiety, depression, somatizations, paranoia, and social withdrawal. Lastly, HRQoL is impaired by co-infections as well as comorbidities. Conclusion: Our preliminary results must be confirmed to deepen the findings between mental health and hemophilia.

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Quality of Life in Hemophilia

Mackensen

Gringeri

2005

Textbook of Hemophilia

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A controlled study of anxiety and morbid cognitions at initial screening for Human Immunodeficiency Virus (HIV) in a cohort of people with haemophilia

Cited by 7 publications

References 34 publications

Health status and satisfaction of asymptomatic HIV‐positive haemophiliacs in Kyushu, Japan

Health status and satisfaction of asymptomatic HIV‐positive haemophiliacs in Kyushu, Japan

Health Related Quality of Life and Psychopathological Symptoms in People With Hemophilia, Bloodborne Co-Infections and Comorbidities: An Italian Multicenter Observational Study

Quality of Life in Hemophilia

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