2024
DOI: 10.3390/bioengineering11060601
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A Convexity-Preserving Level-Set Method for the Segmentation of Tumor Organoids

Xiaoyi Lei,
Luying Gui,
Hairong Liu

Abstract: Tumor organoid cultures play a crucial role in clinical practice, particularly in guiding medication by accurately determining the morphology and size of the organoids. However, segmenting individual tumor organoids is challenging due to their inhomogeneous internal intensity and overlapping structures. This paper proposes a convexity-preserving level-set segmentation 4 model based on the characteristics of tumor organoid images to segment individual tumor organoids precisely. Considering the predominant spher… Show more

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