A Correlation between Carotenemia and Biliary Dyskinesia

Abstract

The interrelationship between carotenemia and biliary dyskinesia was studied in eighty-two biliary dyskinesia patients and twenty-seven normal subjects. Incidence of serum carotene levels of more than 300 micrograms/dl was more frequent in biliary dyskinesia patients without liver damage or hyperlipemia. Among the carotenemia patients, no dietary cases were found, but metabolic and hyperlipemic ones were observed. Significant relationships were found between gall bladder contraction rate and the levels of serum carotene, vitamin A, and lipids in metabolic carotenemia. A close relationship between metabolic carotenemia and biliary dyskinesia was strongly suggested.

Yellow Corneal Ring Associated with Vitamin Supplementation for Age-Related Macular Degeneration

“…Carotenoid pigmentation has also been described in the liver, reflecting the systemic nature of pigment deposition. 26 …”

Xanthoderma: A clinical review

“…15 Although carotenoderma is generally a benign disease, case reports have reported granulocytopenia, biliary dyskinesia, and amenorrhea associated with high levels of serum carotenoids. [30][31][32] Carotenoderma is also associated with a pemphigus-like pattern of immunofluorescence on nonbullous skin, which can theoretically confound the diagnosis of acquired bullous disease in these patients. 33 …”

Quando os vegetais são demais: um caso de carotenodermia

“…Se atingido um valor três a quatro vezes superior, a acumulação na pele torna-se visível e designa-se por carotenodermia. 6 Trata-se de uma situação benigna que afeta sobretudo crianças. As consultas de vigilância de saúde infantil são uma boa oportunidade de identificar estes casos, fazer o aconselhamento dietético adequado e, acima de tudo, tranquilizar os pais/cuidadores.…”

“…Existe associação entre algumas patologias e níveis de carotenos aumentados no sangue. O mecanismo por detrás desta associação resulta de uma diminuição da conversão dos carotenos em vitamina A, levando à sua acumulação e excreção aumentadas; ocorre na diabetes mellitus, discinésia biliar, 6 doença hepática, hipotiroidismo e anorexia nervosa. Estas patologias cursam com o aumento das lipoproteínas no sangue.…”