This study investigates how personality traits relate to burnout among 514 Turkish academics using the “Big Five” and “HEXACO” personality models. Data were collected via online surveys. In the “Big Five personality model”, all traits except emotional stability negatively correlated with burnout. In the “HEXACO personality model”, “honesty-humility”, “extraversion”, “agreeableness”, “conscientiousness”, and “openness to experience” also had negative correlations, while “emotionality” showed a positive correlation with burnout. The “Big Five” personality traits had generally stronger correlations with burnout. This study uniquely compares the “Big Five” with the “HEXACO” personality models.