Psoriasis is a chronic, papulo-squamous, non-infectious, immune-mediated, and inflammatory skin disorder clinically characterized by erythematous sharply demarcated papules and rounded plaques covered by silvery micaceous scales. It is associated with comorbidities such as psoriatic arthritis, depression, obesity, and cardiovascular disease. Psoriasis can also be a source of self and social rejection, thus contributing to stigmatization, alienation, and a decrease in the quality of life (QoL). Due to its complex pathogenesis, a holistic approach is necessary when treating psoriasis. In addition to treating physical symptoms, the patient’s psychological and emotional health should be highly considered to help individuals cope with stigma. Likewise, an increased social awareness of psoriasis may contribute to a better understanding of the disease. Alternative stress management therapies such as spa therapies using dead sea mud and or balneotherapy, yoga, and aromatherapy may be effective in stress management to improve overall well-being and QoL.