2006
DOI: 10.1161/circulationaha.105.000406
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A Critical Reappraisal of the Ross Operation

Abstract: Background-The autograft procedure, an option in aortic valve replacement, has undergone technical evolution. A considerable debate about the most favorable surgical technique in the Ross operation is still ongoing. Originally described as a subcoronary implant, the full root replacement technique is now the most commonly used technique to perform the Ross principle. Methods and Results-Between June of 1994 and June of 2005, the original subcoronary autograft technique was performed in 347 patients. Preoperati… Show more

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Cited by 58 publications
(30 citation statements)
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“…The required sample size of 238 patients in each treatment group was based on the use of a 2-tailed value of Pϭ0.05 to indicate statistical significance for late survival with a minimum power of 0.80. We assumed a late mortality rate of 0.45%/y for patients with the Ross procedure 20 and of 1.40%/y for patients with a mechanical prosthesis 6 with a study duration of 14 years (1994 to 2008) and a constant accrual of patients.…”
Section: Statistical Analysesmentioning
confidence: 99%
“…The required sample size of 238 patients in each treatment group was based on the use of a 2-tailed value of Pϭ0.05 to indicate statistical significance for late survival with a minimum power of 0.80. We assumed a late mortality rate of 0.45%/y for patients with the Ross procedure 20 and of 1.40%/y for patients with a mechanical prosthesis 6 with a study duration of 14 years (1994 to 2008) and a constant accrual of patients.…”
Section: Statistical Analysesmentioning
confidence: 99%
“…Details of the operative techniques have been described elsewhere. [7][8][9] Informed consent was obtained from all patients; the study was approved by the local ethics committee. The authors had full access to and take full responsibility for the integrity of the data.…”
Section: Study Population and Operative Datamentioning
confidence: 99%
“…[1][2][3][4][5] After a renewal of interest in this procedure in the early 90s, long-term results of these procedures are beginning to emerge, and it is well established that autograft function may deteriorate over time eventually requiring replacement. [1][2][3][4][5][6][7][8] Several teams have used autograft reinforcement interventions (R) to treat underlying abnormalities and to stabilize the components of the aortic root 8 -11 in an attempt to prevent autograft failure. These reports include small number of patients and provide short follow-up, which in combination with the low incidence of autograft failure itself may be insufficient to evaluate the effects of such additional procedures.…”
mentioning
confidence: 99%