A Critical Review of Personal Experiences with Craniopharyngioma: Clinical History, Surgical Technique and Operative Results

Raimondi, Anthony J.; Rougerie, J

doi:10.1159/000120827

Cited by 41 publications

(20 citation statements)

References 31 publications

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“…Surgical treatment with craniotomy has been the standard for many years [3,6,7,17,18,22,23]. It is particularly appropriate for suprasellar tumors and allows for visualization of the optic nerves, the optic chiasm, and the relationship of the tumor to these structures and the carotid arteries and the III rd cranial nerve.…”

Section: Treatmentmentioning

confidence: 99%

Craniopharyngioma

2006

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Craniopharyngiomas are benign tumors of the parasellar region. These tumors may be cystic, solid, or combinations of the two. They have a bimodal age distribution and no apparent gender predilection. Patients may present with endocrinopathy or symptoms related to mass effect from the growing tumor. Patients require a multidisciplinary approach during their diagnostic evaluation and subsequent to initiating therapy. Endocrinopathy should be recognized and treated with appropriate hormonal replacement. Surgery is the first-line therapy for most patients. The specific surgical approach must be tailored to the specific clinical situation and depends on the patient age, endocrine status, and the geometry and consistency of the tumor. Whereas most solid tumors will require craniotomy or transsphenoidal surgery, some cystic tumors may be adequately managed with intracavitary therapies. Subtotally resected or residual tumors often require adjuvant radiation therapy or radiosurgery. Long-term multidisciplinary follow-up is necessary for all patients.

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Section: Treatmentmentioning

confidence: 99%

Craniopharyngioma

2006

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“…Although the histology is benign and the mortality rate low, craniopharyngiomas are associated with a high rate of recurrence, which, in turn, is associated with a high rate of morbidity [1]. Although the optimal management of craniopharyngiomas remains controversial, the extent of surgical resection has been considered the most significant predictive factor of tumor cure and good functional outcome [2,3].…”

Section: Introductionmentioning

confidence: 99%

Repeat Operations in Pediatric Patients with Recurrent Craniopharyngiomas

et al. 2009

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Background: Controversy continues over the optimal management of recurrent craniopharyngiomas. Our strategy for approaching repeatedly recurrent craniopharyngiomas in pediatric patients has been to decompress vital structures and relieve the symptoms as early as possible. The purpose of this study was to present our experiences of repeatedly recurrent craniopharyngiomas and the pattern of failure associated with treatment. Methods: A retrospective review was conducted on 7 pediatric patients who underwent resection >2 times in a single institution between 1990 and 2004. Resections were performed 3–8 times for each patient. Variables including tumor size, consistency and location, extent of resection, adjuvant therapy and morbidity were evaluated. Results: Thirty-two operations were performed in 7 pediatric patients. Total resection was not achieved by the third surgery and thereafter, and the interval between each surgery became shorter. Appetite disorders, neurocognitive disorders and behavioral disorders occurred following repeat surgeries. Conclusion: Repeat operations are associated with a high failure rate of tumor control, even though they can help relieve neurologic symptoms. It is suggested that the number of repeat operations should be limited.

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“…9 However, the introduction of computed tomography scanning in the 1970s, followed by magnetic resonance imaging, offered "the closest thing to absolute diagnostic precision ever known for the craniopharyngiomas". 10 In combination with the introduction of microsurgical techniques, this led to significant improvements in peri-operative morbidity and mortality. 11 Radical resection was generally advocated as the treatment of choice for intrasellar and prechiasmatic tumours, with microsurgery offering "an expectation of cure, prevention of recurrence and avoidance of the side effects of radiotherapy".…”

Section: Surgerymentioning

confidence: 99%

Craniopharyngiomas. Historical aspects of their management

Roderick¹,

Karavitaki²,

Wass³

2008

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The history of the management of craniopharyngiomas offers a comprehensive review of the exciting progress in neurosurgery, neuroimaging, neuroendocrinology and radiation oncology during the last century. In this historical note, we present the evolution in management of these most challenging of brain tumours, which, despite the substantial knowledge and expertise gained since the first attempt of surgical removal, remains a subject of considerable debate.

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A Critical Review of Personal Experiences with Craniopharyngioma: Clinical History, Surgical Technique and Operative Results

Cited by 41 publications

References 31 publications

Craniopharyngioma

Craniopharyngioma

Repeat Operations in Pediatric Patients with Recurrent Craniopharyngiomas

Craniopharyngiomas. Historical aspects of their management

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