Significant attention has been given to the development of materials and techniques employed on the additive manufacturing process or also called 3-dimensional printing (3D printing) applied on the construction market. This building technique extrudes cementitious composites to form the contour of the desired geometry. Together with a robotic arm and linked to the blueprints the material is extruded exactly as digitally designed. Therefore, making this building technique a progress on the automation process on the construction industry. In order to have the exact contour as designed for the building, the material used on this application must be developed respecting rigorous rheology parameters. To achieve such high viscosity in cementitious materials, usually viscosity modifiers admixtures (VMA) are employed. One of the commonly used chemical admixtures for this purpose is the hydroxypropyl methylcellulose. However, the consequences of using high content of this admixture in cementitious matrices is still not fully understood. This study characterized the influence of different VMA content on Portland cement paste, by means of a microstructure analysis. The hydration development was assessed, and the influence of the admixture was measured for different curing ages. Important negative side effects were found such as: VMA increasing the cement setting time, different distribution of hydration products on the bulk or increasing the void content. On the other hand, positive effects were also found such as: evidences of internal curing, higher degree of hydration and the lack of undesired hydration products.