A critical review on integrating multiple fish biomarkers as indicator of heavy metals contamination in aquatic ecosystem

Hemmadi, Vijay

doi:10.21746/ijbio.2017.9.5

Cited by 12 publications

(5 citation statements)

References 18 publications

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“…Biomarkers are valuable tools for determining how biological systems interact with potential pollutants (chemical, physical or biological) [7] and, therefore, contribute to evaluating the responses of heavy metals in organisms [8]. Metals can lead to oxidative stress in fish by stimulating the generation of reactive oxygen species (ROS), which damages biological components like lipids, proteins and DNA [9,10].…”

Section: Introductionmentioning

confidence: 99%

Integrated use of biomarkers to assess the impact of heavy metal pollution on Solea aegyptiaca fish in Lake Qarun

et al. 2022

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Background Biomarkers have become a valuable tool in environmental assessment, since they contribute to predicting contaminants in monitoring programmes. This study aimed to investigate the toxicity of heavy metal pollution in Lake Qarun using a multibiomarker approach (morphological, oxidative stress, genotoxicity, stress proteins) in Solea aegyptiaca fish. During the winter and summer seasons, water and fish samples were collected from different locations along Lake Qarun; western and northern sectors were away from any source of pollution, while southern and eastern sectors were exposed to effluents discharged from El-Wadi and El-Bats drains, respectively. The environmental quality, as well as the accumulation of metals (Fe, Cu, Zn, Cd, Pb, Ni) in fish gills, liver, and muscles were assessed. Data were integrated using the integrated biomarker response index (IBRv2) for biomarker response interpretation. Results Water quality and bioaccumulation of heavy metals revealed a highly significant difference between samples collected from polluted sectors and those collected far from drainage water, and, seasonal differences were detected. Growth indices revealed a significant difference between sites and seasons. Fish from the western sector had the highest total antioxidant capacity in their gills, liver, and muscles, with no seasonal differences detected. However, the maximum value of malondialdehyde, protein carbonyl, 8-hydroxy-2′deoxyguanosine, metallothionein, heat shock protein 70, and DNA strand breaks in gills, liver, and muscles was detected in the polluting sectors. It revealed a significant difference between seasons, with the highest value during the winter season. According to IBRv2 results, the most effective biomarkers in this study were malondialdehyde and 8-hydroxy-2′deoxyguanosine in gills, protein carbonyl and metallothionein in the liver, heat shock protein 70 in gills and liver, and DNA strand break in gills, liver, and muscles. Conclusions This multibiomarker approach contributes to distinguishing between locations with varying levels of anthropogenic pollution, identifying the drainage water-exposed sectors as the most stressed and the winter season as the most critical time for Solea aegyptiaca owing to spawning. The biomarkers chosen are effective indicators in Solea aegyptiaca under stress, indicating the potential for environmental monitoring. Graphical Abstract

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Section: Introductionmentioning

confidence: 99%

Integrated use of biomarkers to assess the impact of heavy metal pollution on Solea aegyptiaca fish in Lake Qarun

et al. 2022

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“…Enzyme activities are often regarded as sensitive biochemical indicators for determining the level of tissue damage in exposed organisms (Hemmadi 2017). Despite the difference in the concentration of AST, ALP and ALT, the values were still within a normal range.…”

Section: Discussionmentioning

confidence: 99%

Sub-acute toxicity of hand sanitizer dermal exposure on albino rat (Rattus norvegicus)

Inno-Anaemeje¹,

Dike²,

Babatunde³

2022

TZOOL

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The COVID-19 pandemic resulted in unprecedented awareness and use of hand sanitizer among the populace than seen before. This study used dermal sub-acute toxicity to assess the effect of triclosan-containing hand sanitizer on Rattus norvegicus skin. The research was conducted due to the toxicological and biochemical claims on the effect of triclosan. The study was a 14-day sub-acute dermal toxicity test following the Organization for Economic Cooperation and Development (OECD) guideline on animal testing with preferred test strategy by rubbing to emulate normal hand sanitizer use. The result revealed that triclosan-containing hand sanitizer induced no observable effect on the skin of rats, there was no induced liver dysfunctions, Oestrogen (E2) and Luteinizing hormone levels were normal as in the control. Based on the parameters studied, the hand sanitizers tested is considered safe on skin for consumer use in hand hygiene. It is recommended that more toxicological researches should be carried out on chronic exposures to hand sanitizers, to ensure safety of the populace in compliance with the Sustainable Development Goals

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“…The visceral tissues of fish, such as the liver, kidney, and intestines, which are typically discarded throughout the production procedures, tend to accumulate more metals than the muscles when compared to the other tissues in fish [1,97,99]. Significant correlations between lipid levels and concentrations of critical Cu and Zn [100] in two species of farmed fish (pompano and snapper). According to the research, lipid content may play a significant role in controlling the bioaccumulation of certain metals.…”

Section: Fishmentioning

confidence: 99%

Heavy Metals’ Poisoning in Farm Animals

Acheampong

2023

Heavy Metals - Recent Advances

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Heavy metals are metallic elements with a high density compared to water that are found in trace amounts in a variety of matrices. Mercury poisoning can cause brain damage, skin damage, and increase risk of cancer development. Mercury-poisoned animals cannot produce meat, liver, or kidneys fit for human consumption. Heavy metals can cause cell dysfunction and toxicity by attaching to protein sites and displacing the original metals from their native binding sites. Reducing input/output ratio of heavy metals in animals should be the main objective of effective solutions. Electro-remediation involves running an electric current through liquid manure to cause metal ions to precipitate on an electrode.

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A critical review on integrating multiple fish biomarkers as indicator of heavy metals contamination in aquatic ecosystem

Cited by 12 publications

References 18 publications

Integrated use of biomarkers to assess the impact of heavy metal pollution on Solea aegyptiaca fish in Lake Qarun

Integrated use of biomarkers to assess the impact of heavy metal pollution on Solea aegyptiaca fish in Lake Qarun

Sub-acute toxicity of hand sanitizer dermal exposure on albino rat (Rattus norvegicus)

Heavy Metals’ Poisoning in Farm Animals

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