A cross-sectional MR study of body fat volumes and distribution in chronic schizophrenia

Abstract

People with schizophrenia show higher risk for abdominal obesity than the general population, which could contribute to excess mortality. However, it is unclear whether this is driven by alterations in abdominal fat partitioning. Here, we test the hypothesis that individuals with schizophrenia show a higher proportion of visceral to total body fat measured using magnetic resonance imaging (MRI). We recruited 38 participants with schizophrenia and 38 healthy controls matched on age, sex, ethnicity, and body mass index. We found no significant differences in body fat distribution between groups, suggesting that increased abdominal obesity in schizophrenia is not associated with altered fat distribution.

Somatotype and morphological characteristics of metabolic syndrome in patients with schizophrenia and persons without mental disorders

“…Считается, что данный параметр может выступать надежным предиктором риска развития метаболических нарушений [28]. Существует и противоположная точка зрения, где в ходе исследования не были установлены различия в распределении висцерального жира у лиц с шизофренией, получающих антипсихотическую терапию, и группой контроля по данным магнитно-резонансной томографии [29].…”