A cross-sectional study exploring overlap in post-stroke fatigue caseness using three fatigue instruments: Fatigue Severity Scale, Fatigue Questionnaire and the Lynch’s Clinical Interview

Kjeverud, Anita; Andersson, Stein; Lerdal, Anners; Schanke, Anne‐Kristine; Østlie, Kristin

doi:10.1016/j.jpsychores.2021.110605

Cited by 9 publications

(5 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Chalder Fatigue Scale (CFQ) [ 49 ], has been applied primarily in research into chronic fatigue syndrome (CFS) and myalgic encephalomyelitis (ME), but also in neurological populations such as stroke [ 50 ]. Patients are asked to rate 11 items pertaining to physical and cognitive/mental symptoms of fatigue within the last month.…”

Section: Methodsmentioning

confidence: 99%

Impact of Somatic Vulnerability, Psychosocial Robustness and Injury-Related Factors on Fatigue following Traumatic Brain Injury—A Cross-Sectional Study

Løke

Anđelić

Helseth

et al. 2022

JCM

Self Cite

View full text Add to dashboard Cite

Fatigue is a common symptom after traumatic brain injuries (TBI) and a crucial target of rehabilitation. The subjective and multifactorial nature of fatigue necessitates a biopsychosocial approach in understanding the mechanisms involved in its development. The aim of this study is to provide a comprehensive exploration of factors relevant to identification and rehabilitation of fatigue following TBI. Ninety-six patients with TBI and confirmed intracranial injuries were assessed on average 200 days post-injury with regard to injury-related factors, several patient-reported outcome measures (PROMS) of fatigue, neuropsychological measures, and PROMS of implicated biopsychosocial mechanisms. Factor analytic approaches yielded three underlying factors, termed Psychosocial Robustness, Somatic Vulnerability and Injury Severity. All three dimensions were significantly associated with fatigue in multiple regression analyses and explained 44.2% of variance in fatigue. Post hoc analyses examined univariate contributions of the associations between the factors and fatigue to illuminate the relative contributions of each biopsychosocial variable. Implications for clinical practice and future research are discussed.

show abstract

Section: Methodsmentioning

confidence: 99%

Impact of Somatic Vulnerability, Psychosocial Robustness and Injury-Related Factors on Fatigue following Traumatic Brain Injury—A Cross-Sectional Study

Løke

Anđelić

Helseth

et al. 2022

JCM

Self Cite

View full text Add to dashboard Cite

show abstract

“…Future clinical trials of fatigue management should carefully consider issues, including participant selection and combined intervention development and study design. For participant selection, either the validated case definition for fatigue 34 (noting that this may miss some fatigue cases) 35 or the Greater Manchester Screening tool 12 should be used. Symptoms of depression and anxiety should generally not be exclusion criteria and should be assessed at baseline and follow-up.…”

Section: Resultsmentioning

confidence: 99%

A roadmap for research in post-stroke fatigue: Consensus-based core recommendations from the third Stroke Recovery and Rehabilitation Roundtable

English,

Simpson,

Billinger

et al. 2023

Neurorehabil Neural Repair

Self Cite

View full text Add to dashboard Cite

Rationale: Fatigue affects almost half of all people living with stroke. Stroke survivors rank understanding fatigue and how to reduce it as one of the highest research priorities. Methods: We convened an interdisciplinary, international group of clinical and pre-clinical researchers and lived experience experts. We identified four priority areas: (1) best measurement tools for research, (2) clinical identification of fatigue and potentially modifiable causes, (3) promising interventions and recommendations for future trials, and (4) possible biological mechanisms of fatigue. Cross-cutting themes were aphasia and the voice of people with lived experience. Working parties were formed and structured consensus building processes were followed. Results: We present 20 recommendations covering outcome measures for research, development, and testing of new interventions and priority areas for future research on the biology of post-stroke fatigue. We developed and recommend the use of the Stroke Fatigue Clinical Assessment Tool. Conclusions: By synthesizing current knowledge in post-stroke fatigue across clinical and pre-clinical fields, our work provides a roadmap for future research into post-stroke fatigue.

show abstract

“…Self-reported metrics for pain, fatigue, and mental health measures are all substantially worse compared to the healthy population. For example, the Fatigue Severity Scale yields a score between 1 and 7, with a cut-off score of 4 often used to indicate clinically significant fatigue [45,46]. CCDP Data Registry participants have an average FSS score of 6, indicating most participants are severely fatigued across timepoints.…”

Section: Discussionmentioning

confidence: 99%

Complex Chronic Diseases Program: Program Description & Health Outcomes Assessment from a Clinical Data Registry

Meagher,

Magel,

Boulter

et al. 2024

Preprint

View full text Add to dashboard Cite

Introduction: The Complex Chronic Diseases Program (CCDP) was funded by the BC Ministry of Health to address gaps in health services provision for Complex Chronic Diseases (CCDs). The Program offers medical interventions and education on self-management for people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), Fibromyalgia (FM), and Chronic Lyme-Like Syndrome (CLLS). The CCDP Data Registry was created in 2017 for monitoring participant outcomes and program evaluation. Methods: This research outlined the CCDP model of care and analyzed patient-reported questionnaires and clinical data collected longitudinally from consented CCDP Data Registry participants spanning June 2017 through September 2022. T-tests and linear regression modelling were conducted to ascertain changes in symptom presentation across program involvement. These analyses specifically targeted data at the following time points: baseline, 6 months follow-up, and discharge. Results: Data reported in this study represented 668 eligible participants from the 1-year Program. Demographically, the average age was 49 years old (SD=13), 90% were women (n=557), 54% were diagnosed with ME/CFS and FM (n=360), and 36% reported being on long term illness/disability (n=219). Between baseline and discharge, participants with ME/CFS and FM reported improvements in overall physical and mental health, but no significant improvement in other symptom domains such as sleep, fatigue, and pain. The duration of disease at baseline was only related to sleep quality. The previous, more individualized model of care showed better mental health outcomes at 6-months follow-up. Discussion: This analysis showed that CCDP patients experienced relatively severe and persistent symptom presentations. Participants involved in the Program experienced some health benefits at discharge, but further research and interventions are needed to optimize health outcomes. The reliance on self-report of symptoms and the absence of a control group without intervention limit the significance of these findings. A Strategic Direction Plan was developed by the CCDP which emphasized improved training, decentralized services, fast-tracking of eligible individuals, and enhanced education for better patient outcomes.

show abstract

A cross-sectional study exploring overlap in post-stroke fatigue caseness using three fatigue instruments: Fatigue Severity Scale, Fatigue Questionnaire and the Lynch’s Clinical Interview

Cited by 9 publications

References 30 publications

Impact of Somatic Vulnerability, Psychosocial Robustness and Injury-Related Factors on Fatigue following Traumatic Brain Injury—A Cross-Sectional Study

Impact of Somatic Vulnerability, Psychosocial Robustness and Injury-Related Factors on Fatigue following Traumatic Brain Injury—A Cross-Sectional Study

A roadmap for research in post-stroke fatigue: Consensus-based core recommendations from the third Stroke Recovery and Rehabilitation Roundtable

Complex Chronic Diseases Program: Program Description & Health Outcomes Assessment from a Clinical Data Registry

Contact Info

Product

Resources

About