A Cross-Sectional Study of Medication Adherence Pattern and Factors Affecting the Adherence in Chronic Obstructive Pulmonary Disease

Shrestha, Rajeev; Pant, Anil Dev; Shrestha, Smriti; Shrestha, Bishnu Prasad; Gurung, R

doi:10.3126/kumj.v13i1.13756

Cited by 27 publications

(40 citation statements)

References 57 publications

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“…Results reflected that the highest improvement of medication adherence was seen among young adults (18-35 years) compared to middle and older adults; researchers suggested that this may be due to many of subjects in this age group had a high literacy rate helped them to understand the medication instructions versus to poor medication adherence was found in older adults. These findings were on the line with (Shrestha et al, 2015 andShakya et al, 2016) who found that poor adherence to H. pylori medication was higher in old age compared to young adults, and discussed as elderly people may have more than one chronic illness and use multi drugs that can affect their compliance to H pylori treatment, and they can't tolerate the side effects of the treatment course. Moreover, authors of this research viewed that a high rate of illiteracy and forgetfulness are considered other reasons for missing dose among older people.…”

Section: Discussion: -supporting

confidence: 82%

Educational Intervention for Improving Medication Adherence, Knowledge and Practice Regarding Intrafamilial Transmission among Helicobacter Pylori Patients

Mohammed¹,

Mohammed²,

Fahmy³

2020

Egyptian Journal of Health Care

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Background: The helicobacter pylori (H. pylori) infects more than half of the world's population and associated with the development of 78% of all gastric cancers primarily in developing countries. Patients' education is vital in preventing the intrafamilial transmission as well as in improving medication adherence for H. Pylori eradication therapy. Aim: To investigate the effectiveness of an educational intervention on improving medication adherence, knowledge and practice regarding intrafamilial transmission among helicobacter pylori patients. Methodology: Quasi-experimental research design was utilized. Sample: A purposive sample of two hundred Patients met the following inclusion criteria; patients who aged ≥ 18 yrs. of both sexes, diagnosed as H. pylori infection by positive stool antigen test and under the same strategy of H. pylori eradication therapy. Setting: The current study was carried out at the medical clinic of Minia university hospital, Egypt. Tools of data collection: Two tools were utilized to collect data; 1 st one: Is a Structured interviewing questionnaire sheet covered three parts (Sociodemographic data-knowledge questionnaire related to the H. pylori infection and a self-reported practices regarding its intrafamilial transmission), and the 2 nd one: Medication adherence scale. Results: It was founded that near to three-quarters of the intervention group adhered to H. pylori eradication therapy after the educational intervention compared with only about one-third of the control group. Moreover; there was a significant improvement in the total score of knowledge and practices among the study group regarding H. pylori infection its intrafamilial transmission after receiving educational intervention than before. Conclusion: Application of educational intervention was effective in improving medication adherence, as well as improving the knowledge and practices regarding H. pylori infection and its intrafamilial transmission among infected patients of the study group versus the control group. Recommendations: General population education must be implemented in Egypt, especially among at-risk populations around H. pylori infection and its intrafamilial transmission, as well as the importance of adherence to H. Pylori eradication therapy especially among older adults.

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Section: Discussion: -supporting

confidence: 82%

Educational Intervention for Improving Medication Adherence, Knowledge and Practice Regarding Intrafamilial Transmission among Helicobacter Pylori Patients

Mohammed¹,

Mohammed²,

Fahmy³

2020

Egyptian Journal of Health Care

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“…All these findings are physiologically expected and have been well‐documented in previous studies (Christensen et al, 2016; Ding, Judge, Small, Bent‐Ennakhil, & Siddiqui, 2018; Miravitlles & Ribera, 2017). Increasing age influences medication adherence (Acharya & Sharma, 2019; Krauskopf et al, 2015; Shrestha et al, 2015). In this study, older patients were more adherent to their medications.…”

Section: Discussionmentioning

confidence: 99%

Relationship between symptom burden, medication adherence and spiritual well‐being in patients with chronic obstructive pulmonary disease

Helvaci

İzgü

Özdemir

2020

Journal of Clinical Nursing

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Aims and objectives To investigate the relationship between symptom burden, medication adherence and spiritual well‐being in patients with chronic obstructive pulmonary disease (COPD). Background The relationship between spirituality and medication adherence has been investigated in different chronic conditions. However, the relationship between symptom burden, medication adherence and spiritual well‐being in patients with COPD has not been explored. Design A descriptive correlational study design was adopted. Methods A total of 112 patients with COPD were included in the study. Data were collected using the COPD Assessment Test (CAT), the Adherence to Refills and Medications Scale‐7 (ARMS‐7) and the Functional Assessment of Chronic Illness Therapy‐Spiritual Well‐Being Scale (FACIT‐Sp). The data were analysed using descriptive and correlational statistics. The Strengthening the Reporting of Observational studies in Epidemiology (STROBE) Checklist was used. Results The CAT score was significantly higher in patients on long‐term oxygen therapy and those who had more than three comorbid conditions (p < .05). The mean score of ARMS‐7 was significantly associated with age (p < .05). Current smokers had higher ARMS‐7 and lower FACIT‐Sp scores (p < .001). The FACIT‐Sp score was negatively and moderately associated with the CAT and ARMS‐7 scores (p < .001). Conclusion This study concluded that individuals with higher spiritual well‐being had lower symptom burden and higher medication adherence. The need for long‐term oxygen therapy and a high number of comorbid conditions were associated with increased symptom burden. Current smokers had lower spiritual well‐being and medication adherence. Relevance to clinical practice Spiritual well‐being should be evaluated when assessing symptom burden and medication adherence in clinical practice. In addition, further studies examining the causal relationship between symptom burden, spiritual well‐being and medication adherence in different populations are warranted.

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“… 46 Some studies suggest that older age is a risk factor for non-adherence due to factors such as cognitive impairment, particularly forgetfulness and polypharmacy. 54 A recent study carried out in Saudi Arabia, based on the findings from a National household survey, reported that older age was associated with better treatment adherence in subjects with chronic diseases. 5 It has also been reported that patients with poor adherence often have insufficient understanding of their disease and its management options, and tend to rely more on natural remedies, 55 which could be linked to patient education.…”

Section: Discussionmentioning

confidence: 99%

Adherence to COPD treatment in Turkey and Saudi Arabia: results of the ADCARE study

Köktürk¹,

Polatlı²,

Oğuzülgen³

et al. 2018

COPD

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BackgroundCOPD affects millions of people worldwide. Poor treatment adherence contributes to increased symptom severity, morbidity and mortality. This study was designed to investigate adherence to COPD treatment in Turkey and Saudi Arabia.MethodsAn observational, cross-sectional study in adult COPD patients in Turkey and Saudi Arabia. Through physician-led interviews, data were collected on sociodemographics and disease history, including the impact of COPD on health status using the COPD Assessment Test (CAT); quality of life, using the EuroQol Five-Dimension questionnaire (EQ-5D); and anxiety and depression using the Hospital Anxiety and Depression Scale (HADS). Treatment adherence was measured using the 8-item Morisky Medication Adherence Scale (MMAS-8). Multivariate logistic regression analysis examined the predictors of non-adherence and the impact of adherence on symptom severity.ResultsFour hundred and five COPD patients participated: 199 in Turkey and 206 in Saudi Arabia. Overall, 49.2% reported low adherence (MMAS-8 <6). Of those, 74.7% reported high disease impact (CAT >15) compared to 58.4% reporting medium/high adherence (p=0.0008). Patients with low adherence reported a lower mean 3-level EQ-5D utility value (0.54±0.35) compared to those with medium/high adherence (0.64±0.30; p<0.0001). Depression with HADS score 8–10 or >10 was associated with lower adherence (OR 2.50 [95% CI: 1.43–4.39] and 2.43 [95% CI: 1.39–4.25], respectively; p=0.0008). Being a high school/college graduate was associated with better adherence compared with no high school (OR 0.57 [95% CI: 0.33–0.98] and 0.38 [95% CI: 0.15–1.00], respectively; p=0.0310). After adjusting for age, gender, and country, a significant association between treatment adherence (MMAS-8 score ≥6) and lower disease impact (CAT ≤15) was observed (OR 0.56 [95% CI: 0.33–0.95]; p=0.0314).ConclusionAdherence to COPD treatment is poor in Turkey and Saudi Arabia. Non-adherence to treatment is associated with higher disease impact and reduced quality of life. Depression, age, and level of education were independent determinants of adherence.

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A Cross-Sectional Study of Medication Adherence Pattern and Factors Affecting the Adherence in Chronic Obstructive Pulmonary Disease

Abstract: Background

Cited by 27 publications

References 57 publications

Educational Intervention for Improving Medication Adherence, Knowledge and Practice Regarding Intrafamilial Transmission among Helicobacter Pylori Patients

Educational Intervention for Improving Medication Adherence, Knowledge and Practice Regarding Intrafamilial Transmission among Helicobacter Pylori Patients

Relationship between symptom burden, medication adherence and spiritual well‐being in patients with chronic obstructive pulmonary disease

Adherence to COPD treatment in Turkey and Saudi Arabia: results of the ADCARE study

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