A current review of core decompression in the treatment of osteonecrosis of the femoral head

Abstract

The review describes the following: (1) how traditional core decompression is performed, (2) adjunctive treatments, (3) multiple percutaneous drilling technique, and (4) the overall outcomes of these procedures. Core decompression has optimal outcomes when used in the earliest, precollapse disease stages. More recent studies have reported excellent outcomes with percutaneous drilling. Furthermore, adjunct treatment methods combining core decompression with growth factors, bone morphogenic proteins, stem cells, and bone grafting have demonstrated positive results; however, larger randomized trial is needed to evaluate their overall efficacy.

Platelet‑rich plasma shows beneficial effects for patients with knee osteoarthritis by suppressing inflammatory factors

“…In recent years, non-surgical treatments for knee osteoarthritis have become more widely used, such as PRP, corticosteroid injection and hyaluronic acid (25,28). A previous study described various methods for knee osteoarthritis treatment, including decompression with bone morphogenic proteins, growth factors, bone grafting and stem cells (29). In addition, a systematic review and meta-analysis compared the efficacy of PRP and hyaluronic acid for treatment of knee osteoarthritis and it was demonstrated that PRP injection was more effective than hyaluronic acid in a 2-year meta-analysis (12).…”

Core decompression and biotechnologies in the treatment of avascular necrosis of the femoral head

“…A current review of the literature on CD was published in 2015 by Pierce et al 19 The ideal lesion to be treated with CD is pre-collapse and small. Standard CD procedure is typically performed by the drilling and removal of an 8- to 10-mm cylindrical core from the necrotic lesion.…”

“…Pierce and colleagues showed how more recent studies on CD reported better results than older studies; this could be due to a surgical improvement and a better selection of patients. 19 …”

Platelet-Rich Plasma (PRP) is a New Hope for Patients with Knee Joint Osteoarthritis

“…Therefore, platelets actively participate in healing processes by delivering a broad spectrum of growth factors (insulin like growth factor, transforming growth factor b-I, platelet derived growth factor, and many others) and other active molecules (e.g., arachidonic acid metabolites, cytokines, chemokines, ascorbic acid, extracellular matrix proteins, and nucleotides) to the injured site (26).…”