A current review of pathogenicity determinants of
            <i>Streptococcus</i>
            sp.

Lannes-Costa, Pamella Silva; Oliveira, Jessica Silva Santos de; Santos, Gabriela da Silva; Nagao, Prescilla Emy

doi:10.1111/jam.15090

Cited by 28 publications

(25 citation statements)

References 195 publications

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“…The chosen combination of terms was the most effective in the search for articles related to the question. It was necessary to use the Boolean operator “NOT” for the terms “pyogenes” and “pneumoniae”, which define streptococcal species that do not belong to the viridans group [ 30 ].…”

Section: Discussionmentioning

confidence: 99%

Amoxicillin-Resistant Streptococci Carriage in the Mouths of Children: A Systematic Review and Meta-Analysis

et al. 2022

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Streptococcal bacteremia that occurs during invasive dental procedures can lead to infective endocarditis (IE) in children with certain heart diseases. Prior to such procedures, antibiotic prophylaxis (AP) with amoxicillin (AMPC) is recommended. However, the detection of amoxicillin-resistant strains (AMPC-RS) in the mouths of children with heart diseases raises the concern that they would be uncovered by the action of standard AP. This work carried out a systematic review and meta-analysis regarding AMPC-RS carriage in the mouths of children. We consulted databases covering studies between the years 2000 and 2021, following the PRISMA declaration. A meta-analysis was carried out to assess the prevalence of children carrying AMPC-RS in the mouths. The antimicrobial tests were carried out by microdilution (46.2% of articles), disk diffusion (38.3%), and the E-test (15.4%). Streptococcus mitis and S. sanguinis were bacteria with the most found resistance phenotype, with MIC reaching values of 128 µg/mL. Of the 13 selected articles, only 6 presented results that made it possible to calculate the prevalence of children carrying AMPC-RS in their mouths, ranging from 5.5% to 86.3%. Most of the studies were classified as high quality, and the collected data demonstrate the presence of streptococcal strains with different levels of resistance in the collected samples, such as the dental plaque. The meta-analysis pointed to evidence of AMPC-RS being carried, with a prevalence of 21.3% (I² = 0%, p = 0.705). There is an important prevalence of AMPC-RS carriage in the mouths of children. Specific attention should be directed to AP in those susceptible to IE.

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Section: Discussionmentioning

confidence: 99%

Amoxicillin-Resistant Streptococci Carriage in the Mouths of Children: A Systematic Review and Meta-Analysis

et al. 2022

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“…The Streptococcus species are Gram-positive, spherical, or ovoid cells, which are usually arranged in chains or pairs and widely exist in human feces and nasopharynx ( Lannes-Costa et al, 2021 ). Meta-transcriptomic analysis indicates that the phosphotransferase system is majority expressed by Streptococcus , suggesting that these bacteria are the main utilizers of the available carbohydrates in the small intestinal ( Zoetendal et al, 2012 ).…”

Section: Key Gut Microbes In the Biotransformation Of Natural Productsmentioning

confidence: 99%

Potential roles of gut microbes in biotransformation of natural products: An overview

et al. 2022

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Natural products have been extensively applied in clinical practice, characterized by multi-component and multi-target, many pharmacodynamic substances, complex action mechanisms, and various physiological activities. For the oral administration of natural products, the gut microbiota and clinical efficacy are closely related, but this relationship remains unclear. Gut microbes play an important role in the transformation and utilization of natural products caused by the diversity of enzyme systems. Effective components such as flavonoids, alkaloids, lignans, and phenols cannot be metabolized directly through human digestive enzymes but can be transformed by enzymes produced by gut microorganisms and then utilized. Therefore, the focus is paid to the metabolism of natural products through the gut microbiota. In the present study, we systematically reviewed the studies about gut microbiota and their effect on the biotransformation of various components of natural products and highlighted the involved common bacteria, reaction types, pharmacological actions, and research methods. This study aims to provide theoretical support for the clinical application in the prevention and treatment of diseases and provide new ideas for studying natural products based on gut biotransformation.

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“…agalactiae ) is a species of Gram-positive chain-forming cocci, and is also called group B Streptococcus . It mainly affects humans ( Lannes-Costa et al., 2021 ; Nguyen et al., 2021 ; Tavares et al., 2022 ), cattle ( Keefe, 2012 ; Reyher et al., 2012 ; Kabelitz et al., 2021 ), and fish ( Alazab et al., 2022 ; Piamsomboon et al., 2022 ; Sapugahawatte et al., 2022 ). In dairy animals, S. agalactiae invades the mammary gland, which can lead to clinical or subclinical mastitis; as a result, a reduction in milk production of > 20% is common ( Keefe, 1997 ).…”

Section: Introductionmentioning

confidence: 99%

Molecular epidemiology, drug resistance, and virulence gene analysis of Streptococcus agalactiae isolates from dairy goats in backyard farms in China

Shi

Zhou

Zhang

et al. 2023

Front. Cell. Infect. Microbiol.

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Streptococcus agalactiae infections may lead to clinical or subclinical mastitis in dairy animals when it invades the mammary gland. In this study, 51 S. agalactiae strains were isolated from 305 milk samples that were collected from goats with mastitis in 13 provinces of China. The antimicrobial resistance of S. agalactiae was determined by disk diffusion methods against 18 antibiotics from six classes. In addition, multilocus sequence typing (MLST), and the presence of resistance and virulence genes was determined by PCR analysis. Seven sequence types in five clonal complexes were identified according to MLST; CC103 and CC67 strains were predominant, with rates of 45.1% and 39.2%, respectively. All isolates (100%) were multiresistant to three or more antimicrobial agents. S. agalactiae isolates had a 100% resistance rate to penicillin, oxacillin, and amoxicillin, followed by doxycycline (82.4%), tetracycline (76.5%), and amikacin (74.5%). The lowest resistance was observed for ciprofloxacin (29.4%), which varied in five different regions. The detection rates of six classes of antimicrobial-related genes were calculated as follows: 33 (64.7%) for β-lactam-related resistance gene, 12 (23.5%) for tetracyclines, 11 (21.6%) for quinolone-related resistance genes, 10 (19.6%) for aminoglycosides, 7 (13.7%) for macrolides (ermA, ermB, and mefA), and 3 (5.9%) for lincosamide (lnu(B)). Regarding virulence genes, profile 1 (bca cfb-cspA-cylE-hylB-bibA-pavA-fbsA-fbsB) was the most prevalent, with a detection rate of 54.9%. This work provides a primary source related to the molecular epidemiology of S. agalactiae in dairy goat herds in China and will aid in the clinical treatment, prevention, and control of mastitis.

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A current review of pathogenicity determinants of Streptococcus sp.

Abstract: Article type : Review ArticleA current review of pathogenicity determinants of Streptococcus spp.

Cited by 28 publications

References 195 publications

Amoxicillin-Resistant Streptococci Carriage in the Mouths of Children: A Systematic Review and Meta-Analysis

Amoxicillin-Resistant Streptococci Carriage in the Mouths of Children: A Systematic Review and Meta-Analysis

Potential roles of gut microbes in biotransformation of natural products: An overview

Molecular epidemiology, drug resistance, and virulence gene analysis of Streptococcus agalactiae isolates from dairy goats in backyard farms in China

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