A current update on the phytopharmacological aspects of Houttuynia cordata Thunb

Abstract

The present review is an attempt to put an insight into a medicinal plant Houttuynia cordata Thunb, which is indigenous to North-East India and China. It is an aromatic medicinal herb belonging to family Saururaceae and is restricted to specialized moist habitats. The review provides detailed information regarding the morphology, distribution, phytochemistry, ethnopharmacological uses and also describes various pharmacological activities reported on the plant H. cordata. The review describes therapeutic efficacy of the whole plant and its extracts, fractions and isolated compounds in different diseased condition. Among the important pharmacological activities reported includes, anti-mutagenic, anti-cancer, adjuvanticity, anti-obesity, hepatoprotective, anti-viral, anti-bacterial, anti-inflammatory, free radical scavenging, anti-microbial, anti-allergic, anti-leukemic, chronic sinusitis and nasal polyps activities. Thus, the present review will act as a source of referential information to researchers to perform clinical studies on isolated compounds that may serve the society and will help in improving human health care system.

Effect of dietaryHouttuynia cordataleaf meal and leaf extract on the growth performance, nutrient utilization and expression of IGF‐I gene inLabeo rohita

“…These data are in agreement with the findings of Duan (1998) who proposed that in fish as in mammals, IGF-I plays a central role in the hormonal control of growth. However, H. cordata has been shown to possess anti-hyperglycaemic activity and promote the insulin secretion in rodents (Kumar et al, 2014). Kumar, Prasad, and Hemalatha (2016) reported that H. cordata plant consists of flavonoid compounds mainly quercetin that has potent ability to induce the secretion of insulin and finally that up-regulate the IGF-I expression.…”

First Report on the Ethnopharmacological Uses of Medicinal Plants by Monpa Tribe from the Zemithang Region of Arunachal Pradesh, Eastern Himalayas, India

“…Interestingly, we found that an ethnomedicine named as Bragen (prepared from Bergenia stracheyi as well) was also used for the treatment of arthritis. Recently in 2014, Kumar et al reported that the extracts of Houttuynia cordata can be used for the healing of hemorrhoids, and this species is frequently used in tradtional Tibetan and Chinese medicines [20]. We found that the ethnomedicine Maraptang prepared from Houttuynia cordata were also used by the tradtional Monpa healers for the treatment of piles which is a type of hemorrhoid.…”

The Effects of Houttuynia cordata Thunb and Piper ribesioides Wall Extracts on Breast Carcinoma Cell Proliferation, Migration, Invasion and Apoptosis

“…Many phytochemical compounds in both plants have been reported, such as phenolic acids and alkaloids [7,8]. We investigated the total phenolic acid contents, flavonoids and antioxidant activity, as shown in Table 1.…”

“…There is a long history of herbal medicine plants widely distributed in East Asia, with Chinese people having utilized herbs and plants to treat various diseases for a long time. Moreover, they are intriguing natural products which are widely used as food supplements and to promote health [7]. Furthermore, H. cordata possesses anti-cancer, anti-diabetics, and anti-inflammation properties.…”