“…While numerous studies exist which, in a variety of contexts and disorders, used machine learning to predict individual fatigue levels from behavioural or physiological data (Baykaner et al ., 2015; Mun & Geng, 2019; Luo et al ., 2020; Bafna et al ., 2021; Jiang et al ., 2021; Pinto-Bernal et al ., 2021; Yao et al ., 2021; Zeng et al ., 2021), only two of these studies have concerned MS (Ibrahim et al ., 2020; 2022). Additionally, like the vast majority of studies, these two MS-specific studies did not actually predict fatigue (the subjective experience) but predict fatiguability (the observable decrease in performance during physiologically or cognitively demanding tasks) (Kluger et al, 2013) (sometimes, fatigue and fatiguability are also referred to as “trait fatigue” and “state fatigue”, respectively (Cehelyk et al ., 2019)).…”