A Decade Analysis of Trends and Outcomes of Male vs Female Patients Who Underwent Bariatric Surgery

Young, Monica T.; Phelan, Michael; Nguyen, Ninh T.

doi:10.1016/j.jamcollsurg.2015.11.033

Cited by 119 publications

(71 citation statements)

References 25 publications

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“…The vast majority of recipients of bariatric surgeries are women (>80%) [4] of whom approximately half are of the peri/postmenopausal age [5]. Vertical sleeve gastrectomy (VSG) resects 80% of the stomach, creating a tube linking the esophagus to the duodenum.…”

Section: Introductionmentioning

confidence: 99%

Vertical sleeve gastrectomy improves indices of metabolic disease in rodent model of surgical menopause

Lawson

Shirey²,

Spann³

et al. 2017

Menopause

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Objective Though females are the most common recipients of weight loss surgeries for the amelioration of the comorbidities of obesity, few studies have addressed the efficacy of these procedures with specific attention to reproductive stage. Here we ask in a rodent model of vertical sleeve gastrectomy (VSG) whether improvements to metabolic health are realized in females having received surgical menopause. Specifically we were interested in knowing whether rats made menopausal through surgical means would exhibit persistent hepatic steatosis as reported in previously pregnant, freely-cycling female VSG rats or if it is resolved as reported in male VSG rats. Methods All the rats first received ovariectomy (OVX) and then were placed on high fat diet (HFD) prior to either sham or VSG surgery (N = 12, 9) and then were monitored for resolution of obesity-related comorbidities. Results VSG was sufficient to reduce weight and adiposity in OVX females in comparison to Obese rats (P < 0.001). Glucose tolerance (P < 0.05) was improved in OVX-VSG females with no change in insulin sensitivity. Both circulating (P < 0.01) and hepatic triglyceride (P < 0.01) levels were also reduced after VSG. Liver integrity was improved in OVX-VSG in comparison to OVX-Obese as reflected by reduced aspartate aminotransferase (AST) levels (P < 0.05). The ability of mitochondria to generate ATP was maintained and an increase in complex IV may decrease the production of mitochondrial ROS. Conclusions Taken together, VSG in ovariectomized animals experience many positive benefits including the resolution of hepatic steatosis that persists in reproductively-intact female rats after VSG.

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Section: Introductionmentioning

confidence: 99%

Vertical sleeve gastrectomy improves indices of metabolic disease in rodent model of surgical menopause

Lawson

Shirey²,

Spann³

et al. 2017

Menopause

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“…This may be due to sedentary life style and consuming excessive sweets 14. This is evident in our study by the number of super-obese (22.22%) and super-super-obese (11.11%) patients.…”

Section: Discussionmentioning

confidence: 50%

Revisional laparoscopic sleeve gastrectomy in failed gastric banding and effects of exercise and frequent sweet-eating on its outcome

Al-Wadaani

Qadeer

2017

Pak J Med Sci

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Objective:To find out effectiveness of revisional laparoscopic sleeve gastrectomy (RLSG) in the patients who had laparoscopic adjustable gastric banding (LAGB) and failed to reduce or regained the weight and effectiveness of sweet abstaining and exercise on postoperative weight loss.Methods:This retrospective observational study was conducted at AlMoosa Hospital, Al-Ahsa, Kingdom of Saudi Arabia from December 2011 to November 2016. The patients who failed to reduce, regained the weight or had complications after LAGB, were performed RLSG. They were followed-up at three, six, twelve and twenty-four months intervals. Their weight, percent excess weight loss (%EWL) and body mass index (BMI) at pre-RLSG were compared with post-RLSG. The data was recorded in SPSS 22 and analyzed.Results:Thirty-six patients with male/female ratio of 1:5 underwent RLSG. Twelve (33.3%) were frequent sweet-eaters and twenty-four (66.7%) were not. Fourteen (38.88%) did not have exercise, while twenty-two (61.11%) had daily regular exercise. Their mean pre-RLSG weight, percent excess weight loss (%EWL)and BMI were compared with post-RLSG at the period of three, six, twelve and twenty-four months. Their mean weight reduced from 111.69 kilograms to 96.94, 87.25, 79.56 and 76.11 kilograms respectively. Their mean of the percent excess weight loss (%EWL) reduced to 22.08, 45.75, 59.64 and 66.42 kilograms respectively. Their mean pre-RLSG BMI was 43.50 kg.m-2, which reduced to the mean of 37.79, 34.02, 30.97 and 29.70 respectively. There were no post-operative complications in thirty (83.3%), mild like wound infection and seroma in four (11.1%) and bleeding in two (5.6%) patients. None of the patients had leakage. The patients who kept themselves abstained from sweet consumption and performed regular postoperative exercise had better results. They also had considerable reduction in appetite after RLSG.Conclusion:RLSG is an effective procedure after failed LAGB in terms of weight loss having minimal rate of complications. Moreover, abstaining from sweet consumption and continuing exercise postoperatively has better results.

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“…According to epidemiological data from Brazil [14], where bariatric surgery is very popular, 78% of all bariatric procedures were performed in women, and the average age of patients was 37 years old. Similar demographic data has emerged from an analysis of more than 810,000 bariatric procedures, performed in the United States between 2002-2011 [15], and analysis of 3,039 bariatric surgeries performed in the United Kingdom between 2002-2014 [16].…”

Section: Introductionmentioning

confidence: 72%

The use of contraception for patients after bariatric surgery

Ostrowska

Lech²,

Stefańska³

et al. 2016

Ginekol Pol

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Obesity in women of reproductive age is a serious concern regarding reproductive health. In many cases of infertility in obese women, reduction of body weight may lead to spontaneous pregnancy, without the need for more specific methods of treatment. Bariatric surgery is safe and is the most effective method for body weight reduction in obese and very obese patients. In practice there are two bariatric techniques; gastric banding, which leads to weight loss through intake restriction, and gastric bypass, leads to weight loss through food malabsorption. Gastric bypass surgery (the more frequently performed procedure), in most cases, leads to changes in eating habits and may result in vomiting, diarrhea and rapid body mass reduction. There are reliable data describing the continuous increase in the number of women who are trying to conceive, or are already pregnant, following bariatric surgery. Most medical specialists advise women to avoid pregnancy within 12-18 months after bariatric surgery. This allows for time to recover sufficiency from the decreased absorption of nutrients caused by the bariatric surgery. During this period there is a need for the use of reliable contraception. As there is a risk for malabsorption of hormones taken orally, the combined and progestogen-only pills are contraindicated, and displaced by non-oral hormonal contraception or non-hormonal methods, including intrauterine devices and condoms.

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A Decade Analysis of Trends and Outcomes of Male vs Female Patients Who Underwent Bariatric Surgery

Cited by 119 publications

References 25 publications

Vertical sleeve gastrectomy improves indices of metabolic disease in rodent model of surgical menopause

Vertical sleeve gastrectomy improves indices of metabolic disease in rodent model of surgical menopause

Revisional laparoscopic sleeve gastrectomy in failed gastric banding and effects of exercise and frequent sweet-eating on its outcome

The use of contraception for patients after bariatric surgery

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