3D printing has rapidly evolved and matured in recent years, with a key factor being the improvement in printing materials. This paper compares the performance and applications of various 3D printing materials, including plastics, metals, ceramics, and biomaterials. Plastics remain the most widely used material due to their low cost and ease of printing, while metals are gaining popularity due to their superior mechanical properties. However, recent advancements in ceramic and biomaterials have opened up new possibilities for 3D printing in industries such as aerospace, healthcare, and electronics. The comparative analysis provides insights into the strengths and limitations of each material, and how they can be optimized for specific applications. With continuous developments in 3D printing technology and materials, the potential for this technology to revolutionize manufacturing and other industries is promising.