2010
DOI: 10.2174/092986610790963690
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A Designed β-Hairpin Forming Peptide Undergoes a Consecutive Stepwise Process for Self-Assembly into Nanofibrils

Abstract: We used a de novo designed, beta-hairpin forming T1 peptide as a model to investigate the kinetics of peptide fibrogenesis by a combination of light scattering (LS), circular dichroism (CD), fluorescence, and atomic force microscopy (AFM). The results demonstrate that the T1 fibrogenesis undergoes a consecutive stepwise process, with a high degree of cooperation, presenting sigmoidal time-courses of the peptide aggregation, the subsequent conformational conversion of the backbone, and the peptide sidechains' r… Show more

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Cited by 7 publications
(9 citation statements)
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“…To evaluate the performance of our proposed GBE method, the publicly available reference benchmark of German data set is used [ 31 ], whereas the reference benchmark for Australian data set is obtained using the BARISTA [ 37 ]. In addition, the ISPRS adopted threshold-based evaluation system [ 38 ] and the threshold-free evaluation system [ 39 ] are employed to evaluate the performance.…”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…To evaluate the performance of our proposed GBE method, the publicly available reference benchmark of German data set is used [ 31 ], whereas the reference benchmark for Australian data set is obtained using the BARISTA [ 37 ]. In addition, the ISPRS adopted threshold-based evaluation system [ 38 ] and the threshold-free evaluation system [ 39 ] are employed to evaluate the performance.…”
Section: Methodsmentioning
confidence: 99%
“…If the red colour trees are present in the site, then the red channel is replaced with the green channel to separate the red colour trees from buildings. The provided data sets, i.e., Australian and German data sets [ 31 ], do not have a infrared channel. Therefore, a pseudo-NDVI is used as an alternative index.…”
Section: Related Workmentioning
confidence: 99%
“…The first dataset was collected in the city of Vaihingen, ISPRS dataset [34] and the other set, which has a higher point density, was collected on the Wuhan University campus, China. In the quantitative tests, the reference data were created manually based on the initial segmentation results and aerial images.…”
Section: Datasets and Fundamental Algorithmmentioning
confidence: 99%
“…The authors would like to acknowledge the provision of the Downtown Toronto dataset by Optech Inc., First Base Solutions Inc., York University, and ISPRS WG III/4. The Vaihingen dataset was provided by the German Society for Photogrammetry, Remote Sensing and Geoinformation (DGPF) [ 33 ]. This work was supported by 2014 Research Fund of Myongji University.…”
Section: Acknowledgmentsmentioning
confidence: 99%