A nonlinear model is proposed in light of the theory of isodamage curves, to assess the cumulative fatigue damage under multistage loading. The isodamage curves were developed through the theory of the S-N fatigue damage envelope, proposed by Pavlou. The adopted functional form of the fatigue damage is a commonly accepted general form. In the present work, a stress function for the fatigue life exponent is derived with the aid of the S-N curve only. In the proposed nonlinear model, no adjusting parameters are necessary for fatigue damage estimation. The fatigue life prediction of the derived model is compared with experimental results of various alloys and existing models.