A developmental approach to the prevention of hypertension and kidney disease: a report from the Low Birth Weight and Nephron Number Working Group

Luyckx, Valérie A.; Perico, Norberto; Somaschini, Marco; Manfellotto, Dario; Valensise, H.; Cetin, Irene; Simeoni, Umberto; Allegaert, Karel; Vikse, Bjørn Egil; Steegers, Eric A.P.; Adu, Dwomoa; Montini, Giovanni; Remuzzi, Giuseppe; Brenner, Barry M.; Benedetto, Chiara; Charlton, Jennifer R.; Chevalier, Robert L.; Cortinovis, Monica; D’Anna, Rosario; Duvekot, Johannes J.; Escribano, Joaquín; Fanos, Vassilios; Ferrazzi, Enrico; Frusca, T.; Glassock, Richard J.; Gyselaers, Wilfried; Mecacci, Federico; Osmond, Clive; Ramenghi, Luca A.; Romagnani, Paola; Santoro, Antonio

doi:10.1016/s0140-6736(17)30576-7

Cited by 145 publications

(153 citation statements)

References 29 publications

Supporting

Mentioning

134

Contrasting

Unclassified

Order By: Relevance

“…Animal studies have shown that nephron number can be influenced by an adverse feto-maternal environment, and a developmental contribution to adult hypertension and CKD in humans is becoming increasingly accepted (27,28). We previously reported a direct correlation between total nephron number and birth weight in white and African Americans (14).…”

Section: Discussionmentioning

confidence: 86%

New insights on glomerular hyperfiltration: a Japanese autopsy study

Kanzaki¹,

Puelles²,

Cullen‐McEwen³

et al. 2017

JCI Insight

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 86%

New insights on glomerular hyperfiltration: a Japanese autopsy study

Kanzaki¹,

Puelles²,

Cullen‐McEwen³

et al. 2017

JCI Insight

View full text Add to dashboard Cite

“…They highlight the need to act early to prevent CKD and other related NCD later in life by reducing LBW, SGA, prematurity, and low nephron numbers at birth through coordinated intervention by obstetricians, neonatologists, nephrologists, and family physicians [15,451]. This is particularly relevant for resource-poor countries that experience the burdens of maternal, fetal, and childhood undernutrition and poor health, which synergistically act to augment the effect of developmental programming of chronic diseases, which also disproportionally affects low- and middle-income regions.…”

Section: Discussionmentioning

confidence: 99%

The Impact of Kidney Development on the Life Course: A Consensus Document for Action

Brenner

Charlton

Luyckx

et al. 2017

Nephron

123

View full text Add to dashboard Cite

Hypertension and chronic kidney disease (CKD) have a significant impact on global morbidity and mortality. The Low Birth Weight and Nephron Number Working Group has prepared a consensus document aimed to address the relatively neglected issue for the developmental programming of hypertension and CKD. It emerged from a workshop held on April 2, 2016, including eminent internationally recognized experts in the field of obstetrics, neonatology, and nephrology. Through multidisciplinary engagement, the goal of the workshop was to highlight the association between fetal and childhood development and an increased risk of adult diseases, focusing on hypertension and CKD, and to suggest possible practical solutions for the future. The recommendations for action of the consensus workshop are the results of combined clinical experience, shared research expertise, and a review of the literature. They highlight the need to act early to prevent CKD and other related noncommunicable diseases later in life by reducing low birth weight, small for gestational age, prematurity, and low nephron numbers at birth through coordinated interventions. Meeting the current unmet needs would help to define the most cost-effective strategies and to optimize interventions to limit or interrupt the developmental programming cycle of CKD later in life, especially in the poorest part of the world.

show abstract

“…Estimates indicate that AH was diagnosed at the age of 3 in 7.3% of prematurely born children. The risk of developing AH increases with a younger gestational age and is particularly high in those born before 33 weeks of pregnancy [12].…”

Section: Epidemiology Of Hypertension In Children and Adolescentsmentioning

confidence: 99%

“…These guidelines adopted the management principles published in 2018 by the Polish Neonatological Society and concerning post-hospital care for children born prematurely [5] as well as the Low Birth Weight and Nephron Number Working Group published in 2017 [139]. Children diagnosed with AH before discharge from the neonatal unit should be consulted and provided with specialist care in the paediatric hypertension centre during the hospitalization.…”

Section: Treatment Of Neonatal Hypertensionmentioning

confidence: 99%

Zalecenia Sekcji Pediatrycznej Polskiego Towarzystwa Nadciśnienia Tętniczego dotyczące postępowania diagnostycznego i terapeutycznego w nadciśnieniu tętniczym u dzieci i młodzieży

Litwin

Niemirska

Obrycki

et al. 2018

Arterial Hypertension

View full text Add to dashboard Cite

Presented recommendations are an extended and actualized version of paediatric recommendations of Polish Society of Hypertension published in 2015. Since then, new studies have appeared on this subject, introducing a new classification of hypertension, newly described principles of management in risk groups and methods of assessing hypertensive target organ damage. The presented updated recommendations included changes introduced in the 2016 European Society of Hypertension recommendations and Recommendations of Children's Memorial Health Institute in Warsaw. Recently published guidelines of American Academy of Pediatrics have been discussed. In the presented issue of guidelines, epidemiological information on the occurrence and incidence of hypertension in developmental age was added and classification of blood pressure values was updated. Subchapters on diagnosis and organ damage assessment, principles of diagnosis and treatment of hypertension in children with diabetes, chronic kidney disease and a subsection discussing diagnostic and therapeutic difficulties with setting blood pressure targets were revised. In addition, the principles of early diagnosis of arterial hypertension in post-hospital care in children born before 33 weeks of gestation published in 2018 as recommendations of the Polish Neonatal Society have been also taken into account.

show abstract

A developmental approach to the prevention of hypertension and kidney disease: a report from the Low Birth Weight and Nephron Number Working Group

Cited by 145 publications

References 29 publications

New insights on glomerular hyperfiltration: a Japanese autopsy study

New insights on glomerular hyperfiltration: a Japanese autopsy study

The Impact of Kidney Development on the Life Course: A Consensus Document for Action

Zalecenia Sekcji Pediatrycznej Polskiego Towarzystwa Nadciśnienia Tętniczego dotyczące postępowania diagnostycznego i terapeutycznego w nadciśnieniu tętniczym u dzieci i młodzieży

Contact Info

Product

Resources

About