A Diagnostic Accuracy Meta-analysis of CT and MRI for the Evaluation of Small Bowel Crohn Disease

Liu, Wenhong; Liu, Jincai; Wen-lian, Xiao; Luo, Guanghua

doi:10.1016/j.acra.2017.04.013

Cited by 52 publications

(36 citation statements)

References 29 publications

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“…A higher b-value (3,000 sec/mm 2 ) for DWI revealed the specificity for distinguishing neoplasms from bowel inflammation to be increased, with 76% of the positive findings representing neoplasms. DWI has been widely used for the assessment of bowel diseases in recent years; however, the majority of studies have investigated the detection of neoplasms or inflamed bowel loops from normal loops using lower b-values (18,23,(27)(28)(29). However, while the differentiation between bowel inflammation and neoplasms is clinically useful, it remains challenging when lower b values DWI are used, as neoplasms and inflammation are detected with high intensities at b-values between 400-1,200 sec/mm 2 .…”

Section: Discussionmentioning

confidence: 99%

Potential of diffusion‑weighted imaging in magnetic resonance enterography to identify neoplasms in the ileocecal region: Use of ultra‑high b‑value diffusion‑weighted imaging

Feng

Wang

et al. 2019

Oncol Lett

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Patients with chronic inflammatory bowel disease have an increased risk of colorectal cancer, and the differentiation between neoplastic and inflammatory lesions often poses a clinical dilemma. The aim of the present study was to investigate whether diffusion-weighted (DW) magnetic resonance (MR) enterography with ultra-high b-value facilitates the identification of neoplastic lesions in the ileocecal region. A total of 76 patients (22 patients with neoplasms, 26 inflammatory lesions and 28 normal subjects) from 292 cases of suspected bowel disorders were included in the present study. All patients were examined with conventional MR enterography and DW imaging (DWI) with seven different b-values (400, 600, 800, 1,000, 1,200, 1,500 and 3,000 sec/mm 2 ) in a 3T MR scanner. DWI scans with different b-values were analyzed independently by two radiologists for the presence of ileocecal lesions. The signal intensity of the majority of inflammatory lesions and normal bowel segments gradually decreased to the background intensity with increasing b-values; however, neoplastic lesions demonstrated relative hyperintensity compared with the background. In addition, ~76% of the positive findings from b=3,000 sec/mm 2 DWI were neoplasms. In conclusion, a lesion with consistently high signal intensity from DWI images with b-values increasing to 3,000 sec/mm 2 indicated the presence of neoplasms. The results suggested that ultra-high b-value (3,000 sec/mm 2 ) imaging may aid the clinical differentiation of neoplasms from benign conditions.

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Section: Discussionmentioning

confidence: 99%

Potential of diffusion‑weighted imaging in magnetic resonance enterography to identify neoplasms in the ileocecal region: Use of ultra‑high b‑value diffusion‑weighted imaging

Feng

Wang

et al. 2019

Oncol Lett

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“…A recent metaanalysis suggests that both modalities possess a high diagnos-tic accuracy in detecting small bowel disease, but MR enterography has the advantage of being a radiation-free modality. 13 In multivariate analysis, small stricture luminal diameter and increased stricture wall thickness were predictors of strictures for which medical therapy typically fails. 14 The patients should be educated about their disease and the operative options because they commonly possess only rudimentary insight.…”

Section: Preoperative Evaluation and Optimizationmentioning

confidence: 96%

Strictureplasty in Complex Crohn's Disease: Beyond the Basics

Strong

2019

Clinics in Colon and Rectal Surgery

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“…In einer rezenten Metaanalyse wurde berichtete, dass MR-Enterographie, MREnteroklysma und CT-Enterographie eine vergleichbare Genauigkeit in der Detektion eines M. Crohn aufweisen [13]. Die MR-Enterographie und das MR-Enteroklysma ermöglichen jedoch eine Beurteilung der Aktivität bzw.…”

Section: Mr-enterographieunclassified

“…Die MR-Enterographie und das MR-Enteroklysma ermöglichen jedoch eine Beurteilung der Aktivität bzw. der Subtypen der Erkrankung [13]. Die Gefahr einer inkompletten Füllung ist bei der MR-Enterographie höher als beim MR-Enteroklysma [3,20].…”

Section: Mr-enterographieunclassified

Radiologische Charakterisierung chronisch-entzündlicher Darmerkrankungen

Schöllnast

2018

Radiologe

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A Diagnostic Accuracy Meta-analysis of CT and MRI for the Evaluation of Small Bowel Crohn Disease

Cited by 52 publications

References 29 publications

Potential of diffusion‑weighted imaging in magnetic resonance enterography to identify neoplasms in the ileocecal region: Use of ultra‑high b‑value diffusion‑weighted imaging

Potential of diffusion‑weighted imaging in magnetic resonance enterography to identify neoplasms in the ileocecal region: Use of ultra‑high b‑value diffusion‑weighted imaging

Strictureplasty in Complex Crohn's Disease: Beyond the Basics

Radiologische Charakterisierung chronisch-entzündlicher Darmerkrankungen

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