GPS is well recognized as the best procedure for outdoor localization. However, it presents limits in indoor localization due to particular geometric difficulties that necessitate specific solution to locate a target inside a building. Also, radio frequency technologies have many disadvantages in indoor localization. Bluetooth and Radio Frequency Identification (RFID) are unsuitable for realtime localization because of latency. Ultra-wideband (UWB) localization needs an expensive hardware. Zigbee presents a high interference with wide range of signal frequency because it operates in unlicensed Industrial, Scientific and Medical ISM bands. Light waves also present some limitations due to interferences from fluorescent light and sunlight. The IR based indoor system has expensive system hardware and maintenance cost. To overcome limits and non-availability of radio waves and light waves, an acoustic solution using an array of microphones is presented as a solution for indoor localization, and an optimized deployment is used to improve precision and restrain error. The aim of this work is to propose a 3D indoor audio localization approach inspired by the principle of functioning of the human ear. In order to achieve our goal, we will use a genetic algorithm to obtain the optimized deployment of the used hardware.