In order to solve the problem of unmeasurable assembly performance of complex product, the digital twin-driven assembly quality control and prediction of complex product is studied by means of cyber-physical fusion in the assembly workshop. The connotation of digital twin intelligent assembly is introduced, the current research status of complex product assembly quality is compared and analyzed, and three main key technologies for the assembly quality control of complex product are proposed: (1) multidimensional, multi-scale, multidisciplinary modeling and simulating of digital twin-driven assembly; (2) multi-source heterogeneous data collection, sensing and fusion for assembly processes; (3) data-driven decision making, feedback and optimization technology. Finally, the application of digital twin technology in the field of assembly quality control of complex product is prospected.