Flexible microfluidic pressure sensors have recently attracted a lot of attention due to its revolutionary potential in the field of healthcare. These sensors provide non-invasive, highly sensitive, and adaptable options for tracking various aspects of human movement and health. Nevertheless, there are a number of limitations that affect the effectiveness of microfluidic pressure sensors, including material selection, sensor packaging techniques, sensitivity, and stability. The research outlined in this paper, which aims to address these issues head-on and significantly improve the functionality of microfluidic pressure sensors in order to increase their usefulness in the fields of medical and biomedical applications.