2007
DOI: 10.1007/s11745-006-3007-3
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A Docosahexaenoic Acid‐Functional Food During Pregnancy Benefits Infant Visual Acuity at Four but not Six Months of Age

Abstract: Within the visual system, docosahexaenoic acid (DHA, 22:6n-3) is an important structural component for retinal photoreceptors and cortical gray matter. There is a marked decrease in neural DHA accumulation in the face of DHA deficiency. DHA is accumulated at an accelerated rate during pregnancy, especially in the third trimester. However, pregnant women in the US and Canada have dietary DHA intakes that are significantly below the optimal level. The main objective of this study was to determine whether a DHA-f… Show more

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Cited by 109 publications
(90 citation statements)
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“…Only a few studies have addressed whether maternal n-3 fatty acid supplementation or intake might benefit offspring cognition. Three randomized trials of prenatal n-3 supplementation suggest improvements in child outcomes in infancy and early childhood [16][17][18][19]. Some observational studies have also found that umbilical cord tissue or blood levels of DHA were associated with better development in infants [15•].…”
Section: Integrative Analysis Of the Overall Effect Of Prenatal Mercumentioning
confidence: 99%
“…Only a few studies have addressed whether maternal n-3 fatty acid supplementation or intake might benefit offspring cognition. Three randomized trials of prenatal n-3 supplementation suggest improvements in child outcomes in infancy and early childhood [16][17][18][19]. Some observational studies have also found that umbilical cord tissue or blood levels of DHA were associated with better development in infants [15•].…”
Section: Integrative Analysis Of the Overall Effect Of Prenatal Mercumentioning
confidence: 99%
“…21 A recent study has demonstrated that DHA supplemented during pregnancy plays a role in the maturation of the visual system and benefits infant visual acuity at 4 but not 6 months of age. 38 Also, results of a recent study indicate that DHA consumption in pregnancy significantly affects problem solving abilities at the age of 9 months, but does not affect memory processes. 39 Additionally, children's mental processing scores at 4 years of age correlated significantly with maternal intake of DHA during pregnancy.…”
Section: Fetal and Maternal Physiology And Ultrasound Diagnosismentioning
confidence: 99%
“…Recent data have confirmed a great impact of maternal diet during pregnancy on fetal growth and development, as well as on postnatal development and health. [34][35][36][37][38][39][40][41][42][43] It is during intrauterine life that the diet has significant effect on the brain development. It has been known for some time that folic acid plays a protective role in neurodevelopmental processes.…”
mentioning
confidence: 99%
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“…Several trials reported other measures of neurodevelopment which included BAEPs (Stein et al, 2012), the Fagan Test of Infant Intelligence (Helland et al, 2001;Judge et al, 2007), the Hempel neonatal neurologic examination (van Goor et al, 2010), and EEG recording (Helland et al, 2001). No significant differences between the treatment groups were observed on any of these measures.…”
Section: Intervention Studies With N-3 Lcpufa Supplementation During mentioning
confidence: 99%