A double-blind comparison of the efficacy of a salicylic acid based acne treatment regimen versus a benzoyl peroxide based acne treatment regimen for the treatment of acne vulgaris

Christine, Jacobson C.; Arambula, Karina; Chon, Susan Y.; Kimball, Alexa B.

doi:10.1016/j.jaad.2003.10.055

Cited by 2 publications

(5 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Additionally, it is important to protect the skin from sun damage by using a broad-spectrum sunscreen with at least SPF 30. Sunscreen helps prevent the darkening of acne scars and reduces the risk of skin cancer [19]. It is also advisable to avoid touching or picking acne as this can introduce bacteria and lead to further inflammation.…”

Section: Acne Treatmentmentioning

confidence: 99%

“…A comprehensive approach that combines medication, skincare, and lifestyle modifications is crucial for effectively managing acne in women [11]. This includes using gentle exfoliants, avoiding irritants, wearing sunscreen, engaging in regular exercise, and maintaining a balanced diet rich in fruits and vegetables [19]. Educating patients about the negative effects of picking or popping pimples can encourage proper skincare practises and prevent scarring or infection.…”

Section: Combined Oral Contraceptivesmentioning

confidence: 99%

“…Consistently following a skincare routine and seeking professional help can help maintain a clearer complexion. However, individual skin types and responses to skincare routines can vary greatly, and some individuals may still experience new blackheads due to factors such as hormonal changes, genetics, or environmental factors [19]. Blackheads, also referred to as “open comedones” are the result of clogged pores that leave clusters of oil and dead skin cells exposed to the air.…”

Section: Main Textmentioning

confidence: 99%

“…Retinoids, derived from vitamin A, help unclog pores and promote cell turnover. These ingredients can be found in prescription‐strength creams or gels as well as some over‐the‐counter products [19]. The choice of treatment depends on the individual's specific needs and the severity of their acne.…”

Section: Acne Treatmentmentioning

confidence: 99%

See 3 more Smart Citations

Cystic acne treatment: A comprehensive review

Durairaj,

Elumalai,

Shanmugam

2023

Medicine Advances

View full text Add to dashboard Cite

Acne, a common skin condition, is primarily seen in teenagers and young adults and is characterised by large pus‐filled bumps beneath the skin. Cystic acne is a common form and is linked to a high incidence of acne‐related skin diseases. Causes include age, sex, and lifestyle changes. Treatment options for severe acne include medications, laser therapy, chemical peels, and microneedling patches. This review focuses on cystic acne treatment options and discusses their advantages and disadvantages. Medications like isotretinoin reduce inflammation but have side effects. Laser therapy targets bacteria without medication but may require multiple sessions for optimal results.

show abstract

Section: Acne Treatmentmentioning

confidence: 99%

Section: Combined Oral Contraceptivesmentioning

confidence: 99%

Section: Main Textmentioning

confidence: 99%

Section: Acne Treatmentmentioning

confidence: 99%

See 2 more Smart Citations

Cystic acne treatment: A comprehensive review

Durairaj,

Elumalai,

Shanmugam

2023

Medicine Advances

View full text Add to dashboard Cite

show abstract

“…Salicylic acid as an active ingredient with keratoplastic action in a small concentration up to 1% is notably recognized for its effects in dermatologic disorders [5]. In acne pathology, SA can exert a double mechanistic action at skin level expressed as a decrease of lipid production, with a reduction of inflammatory events responsible for typical skin erythema [14,37]. Observed from a physicochemical point of view, SA encounters formulation challenges which are attributed to its poor solubility in water [28].…”

Section: Introductionmentioning

confidence: 99%

Preliminary Study Regarding the Formulation and Physical Evaluation of Some Biocompatible, Oil in Water Microemulsions With Salicylic Acid for Dermatologic Use

Anicescu¹

2021

FARMACIA

View full text Add to dashboard Cite

Microemulsions (MEs) are considered a piece of new generation colloidal systems with high potential for drug delivery, especially for topical application. The present study had as main objectives the development and physical analysis of two groups of oil in water (O/W) microemulsion (ME) vehicles using a biocompatible mixture composed of lecithin/Tween 80 as surfactants and propylene glycol (PG) as cosurfactant. The addition of vegetable oils and hyaluronic acid (HA) enriched the quality profile of the systems. The vehicles were suitable to entrap salicylic acid (SA) 0.5% as a model drug with keratoplastic properties, and positive outcomes in acne treatment. The study was divided in two stages of screening, resulting two groups of MEs. In the first case, lecithin was tested as potential surfactant on a domain of 0.5 -2%. A minimum amount of lecithin 0.5%, in association with Tween 80 and PG was considered appropriate to obtain the second group of O/W MEs. In this case, were screened combinations of lecithin/Tween 80/PG able to solubilize SA 0.5% and small quantities of vegetable oils. All the microdispersions obtained in both stages were analysed considering visual appearance, conductivity, pH and refractive index as important parameters for systems' stability. The area of MEs generation for the second group, was specifically identified using graphical method. An extensive rheological analysis was considered to determine the flow behaviour for the most representative systems. It was concluded that minimal concentration of tensioactives that can promote stable and clear systems with SA was 30.5%. This proportion was specific for a ME system formulated with 20% Tween 80, 10%PG and 0.5% lecithin. Physical analysis performance emphasized preliminary data concerning the internal structure of microemulsions, offering a useful background for future studies. RezumatMicroemulsiile (MEs) reprezintă formulări ce aparţin noii generaţii de sisteme coloidale, cu înalt potenţial pentru cedarea medicamentului, în special pentru administrarea topică. Prezentul studiu a avut ca obiective principale dezvoltarea şi analiza fizică a două grupe de vehicule de tip microemulsie (ME) ulei în apă (U/A), utilizând un amestec biocompatibil format din lecitină/Tween 80 ca surfactanţi, alături de propilenglicol (PG) cu funcţie de cosurfactant. Au fost adăugate uleiuri vegetale şi acid hialuronic (HA), cu scopul de a îmbunătăţi profilul calitativ al sistemelor. Vehiculele formulate au fost adecvate pentru încorporarea acidului salicilic (SA) 0,5% ca medicament model cu proprietăţi keratoplastice și efecte pozitive în tratamentul acneei. Studiul a fost împărțit în două etape de screening, rezultând două grupe de microemulsii. În prima etapă, lecitina a fost testată ca potențial surfactant pe un domeniu de 0,5 -2%. Utilizarea lecitinei 0,5%, alături de Tween 80 și PG, a fost considerată potrivită pentru obținerea celui de-al doilea set de sisteme U/A. În acest caz, au fost testate combinații conținând lecitină/Tween 80/PG, capabile să solubilize...

show abstract

A double-blind comparison of the efficacy of a salicylic acid based acne treatment regimen versus a benzoyl peroxide based acne treatment regimen for the treatment of acne vulgaris

Cited by 2 publications

References 0 publications

Cystic acne treatment: A comprehensive review

Cystic acne treatment: A comprehensive review

Preliminary Study Regarding the Formulation and Physical Evaluation of Some Biocompatible, Oil in Water Microemulsions With Salicylic Acid for Dermatologic Use

Contact Info

Product

Resources

About