A Double-Blind Study of Topical Massage with Rado-Salil® Ointment in Mechanical Low-Back Pain

Ginsberg, Francis; Famaey, Jean Pierre

doi:10.1177/030006058701500304

Cited by 26 publications

(33 citation statements)

References 8 publications

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“…1728 Three were active controlled trials and were not included in the meta-analysis 20 27 28. Two additional reports in acute conditions contained extractable information for only adverse events 29 30…”

Section: Resultsmentioning

confidence: 99%

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Systematic review of efficacy of topical rubefacients containing salicylates for the treatment of acute and chronic pain

Mason

Moore

Edwards

et al. 2004

BMJ

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Objective To determine the efficacy and safety of topical rubefacients containing salicylates in acute and chronic pain. Data sources Electronic databases and manufacturers of salicylates. Study selection Randomised double blind trials comparing topical rubefacients with placebo or another active treatment, in adults with acute or chronic pain, and reporting dichotomous information, around a 50% reduction in pain, and analyses at one week for acute conditions and two weeks for chronic conditions.

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Section: Resultsmentioning

confidence: 99%

“…Three placebo controlled trials had information on 182 patients with acute pain,17 – 19 one of which had a low validity score 18. The mean treatment response rate (percentage of patients with at least 50% pain relief) was 67% (range 25% to 90% in individual trials).…”

Section: Resultsmentioning

confidence: 99%

Systematic review of efficacy of topical rubefacients containing salicylates for the treatment of acute and chronic pain

Mason

Moore

Edwards

et al. 2004

BMJ

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“…Results indicated that active treatment produced significant improvements in spontaneous pain, muscular contracture, and in both the patient's and physician's opinions about treatment. These improvements occurred by day 3 and persisted through day 14 53 . While this trial did include a placebo control group, it is important to note that blinding is difficult because of the heat sensation resulting from capsaicin treatment.…”

Section: Capsaicinmentioning

confidence: 84%

Acute back pain: benefits and risks of current treatments

McCarberg

2009

Current Medical Research and Opinion

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“…Both of the reviews were published in the Cochrane library and had strong methods and were well reported. These reviews included several randomized controlled trials including a herbal medicine [19][20][21][22][23][24][25][26][27]. Our search for randomized controlled trials resulted in the identification of 149 titles and upon reviewing abstracts and full texts 145 were excluded for various reasons including: not being an RCT, not including a population suffering from chronic NSLBP, not testing an herbal medicine or nutritional supplement, or being included in one of the reviews above.…”

Section: Results Of Literature Searchmentioning

confidence: 99%

“…One review reports on one small RCT including patients with acute NSLBP [23], though the actual duration of LBP in this study was not described. This review also described another RCT ( N=154) which found that a plaster of Capsicum frutescens with 11 mg capsaicinoids reduces pain and improves function more than placebo for the treatment of acute episodes of chronic non-specific LBP in the shortterm [24].…”

Section: Capsicum Frutescens Versus Placebo [12]mentioning

confidence: 99%

Evidence Based Review of Natural Health Products for Non-Specific Low Back Pain

Gagnier¹

2010

TOPAINJ

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Introduction -Natural health products (e.g., vitamins, minerals, herbal medicines) are frequently used for musculoskeletal pain and there is an increasing amount of high quality research being done to test the efficacy of these interventions. Low back pain is a very common condition and individuals suffering from these conditions are frequently seeking out these products.Objective -The objective of this paper is to review and summarize the evidence surrounding natural health products for chronic non-specific low back pain.Methods -We searched for systematic reviews and randomized controlled trials in PubMed and the Cochrane Library. We performed a best evidence synthesis of the resulting papers.Results -We included two systematic reviews and 2 additional randomized controlled trials published subsequently to these reviews. We found strong evidence for 50 mg harpagoside per dose of an aqueous extract of Harpagophytum procumbens per day reduces pain more than placebo. We found moderate evidence for 100 mg harpagoside per dose of an aqueous extract of Harpagophytum procumbens compared to placebo, for an extract of willow bark yielding 120 mg salicin per day compared with placebo, for 240 mg of salicin per day in reducing pain to a greater extent than placebo, for 240 mg of salicin per day as equivalent to 120 mg salicin, for no differences in pain and function between a 60 mg daily harpagoside dose of an aqueous extract of Harpagophytum procumbens and 12.5 mg rofecoxib per day, for no difference in pain and overall improvement between Spiroflor SRL homeopathic gel (SRL) and Cremor Capsici Compositus FNA, the capsici oleoresin gel, for intramuscular B12 when compared with placebo. We found limited evidence for topical Capsicum frutescens in the form of Rado-Salil cream or a Capsicum plaster for reducing pain more than placebo, for lavender oil in the treatment of chronic NSLBP, or vitamin C, zinc, and manganese in addition to prolotherapy. Adverse events for all interventions appeared to be mild and transient though we did not attempt to identify all relevant literature concerning adverse events.Conclusions -There is some evidence for several natural health products in the treatment of chronic non-specific low back pain. More research is needed for all of these interventions before they are incorporated into routine clinical practice and their reporting must be improved by referring to the recently published extensions of the CONSORT statement.

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A Double-Blind Study of Topical Massage with Rado-Salil® Ointment in Mechanical Low-Back Pain

Cited by 26 publications

References 8 publications

Systematic review of efficacy of topical rubefacients containing salicylates for the treatment of acute and chronic pain

Systematic review of efficacy of topical rubefacients containing salicylates for the treatment of acute and chronic pain

Acute back pain: benefits and risks of current treatments

Evidence Based Review of Natural Health Products for Non-Specific Low Back Pain

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